Gene description for SELP
Gene name	selectin P
Gene symbol	SELP
Other names/aliases	CD62 CD62P GMP140 GRMP LECAM3 PADGEM PSEL
Species	Homo sapiens
Experiment description of studies that identified SELP in Platelets
1 Experiment ID 31 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Immunoelectron Microscopy PubMed ID 10572093    Organism Homo sapiens Experiment description Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules. Authors Heijnen HF, Schiel AE, Fijnheer R, Geuze HJ, Sixma JJ Journal name BLOOD Publication year 1999 Sample Platelets Sample name Platelets Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.14-1.18 g/mL Molecules identified in the study Protein Methods used in the study Western blotting FACS Immunoelectron microscopy EV-TRACK -
2 Experiment ID 369 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 16212402    Organism Homo sapiens Experiment description The platelet microparticle proteome. Authors Garcia BA, Smalley DM, Cho H, Shabanowitz J, Ley K, Hunt DF. Journal name J Proteome Res Publication year 2005 Sample Platelets Sample name Normal donors-Platelets Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
3 Experiment ID 520 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 23601281    Organism Homo sapiens Experiment description Proteomic characterization of human platelet-derived microparticles. Authors Capriotti AL, Caruso G, Cavaliere C, Piovesana S, Samperi R, Laganà A. Journal name Anal Chim Acta Publication year 2013 Sample Platelets Sample name Platelets purifird from blood Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
4 Experiment ID 1344 Identified molecule protein Extracellular vesicle type Platelet-derived microparticles MISEV EV-like nanoparticles Identification method Flow cytometry PubMed ID 33009394    Organism Homo sapiens Experiment description Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p Authors Qu M, Zou X, Fang F, Wang S, Xu L, Zeng Q, Fan Z, Chen L, Yue W, Xie X, Pei X. Journal name Nat Commun Publication year 2020 Sample Platelets Sample name Platelets derived from umbilical cord blood Isolation/purification methods Ficoll-Hypaque density gradient centrifugation Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Flow cytometry Western blotting qPCR EV-TRACK -
5 Experiment ID 2529 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Large EVs Identification method Flow cytometry PubMed ID 34293122    Organism Homo sapiens Experiment description Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Authors Marcoux G, Laroche A, Hasse S, Bellio M, Mbarik M, Tamagne M, Allaeys I, Zufferey A, Lévesque T, Rebetz J, Karakeussian-Rimbaud A, Turgeon J, Bourgoin SG, Hamzeh-Cognasse H, Cognasse F, Kapur R, Semple JW, Hébert MJ, Pirenne F, Overkleeft HS, Florea BI, Dieude M, Vingert B, Boilard E. Journal name Blood Publication year 2021 Sample Platelets Sample name Platelets (thrombin-activated) - healthy volunteers Isolation/purification methods Centrifugation Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Western blotting Immuno-EM Flow cytometry EV-TRACK -
6 Experiment ID 3495 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Flow cytometry PubMed ID 31160588    Organism Homo sapiens Experiment description Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Authors Sung PS, Huang TF, Hsieh SL. Journal name Nat Commun Publication year 2019 Sample Platelets Sample name Peripheral blood of healthy donors Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Flow cytometry EV-TRACK -
7 Experiment ID 3496 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Flow cytometry PubMed ID 31160588    Organism Homo sapiens Experiment description Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Authors Sung PS, Huang TF, Hsieh SL. Journal name Nat Commun Publication year 2019 Sample Platelets Sample name Peripheral blood of healthy donors Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Flow cytometry EV-TRACK -
8 Experiment ID 3497 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Flow cytometry PubMed ID 31160588    Organism Homo sapiens Experiment description Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Authors Sung PS, Huang TF, Hsieh SL. Journal name Nat Commun Publication year 2019 Sample Platelets Sample name Peripheral blood of healthy donors Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Flow cytometry EV-TRACK -
9 Experiment ID 3498 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Flow cytometry PubMed ID 31160588    Organism Homo sapiens Experiment description Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Authors Sung PS, Huang TF, Hsieh SL. Journal name Nat Commun Publication year 2019 Sample Platelets Sample name Peripheral blood of healthy donors Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Flow cytometry EV-TRACK -
10 Experiment ID 3499 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Flow cytometry PubMed ID 31160588    Organism Homo sapiens Experiment description Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Authors Sung PS, Huang TF, Hsieh SL. Journal name Nat Commun Publication year 2019 Sample Platelets Sample name Peripheral blood of healthy donors Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Flow cytometry EV-TRACK -
11 Experiment ID 3500 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Flow cytometry PubMed ID 31160588    Organism Homo sapiens Experiment description Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Authors Sung PS, Huang TF, Hsieh SL. Journal name Nat Commun Publication year 2019 Sample Platelets Sample name Peripheral blood of healthy donors Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Flow cytometry EV-TRACK -
12 Experiment ID 3501 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Flow cytometry PubMed ID 31160588    Organism Homo sapiens Experiment description Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Authors Sung PS, Huang TF, Hsieh SL. Journal name Nat Commun Publication year 2019 Sample Platelets Sample name Peripheral blood of healthy donors Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Flow cytometry EV-TRACK -
13 Experiment ID 3502 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Flow cytometry PubMed ID 31160588    Organism Homo sapiens Experiment description Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Authors Sung PS, Huang TF, Hsieh SL. Journal name Nat Commun Publication year 2019 Sample Platelets Sample name Peripheral blood of healthy donors Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Flow cytometry EV-TRACK -
14 Experiment ID 3503 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Flow cytometry PubMed ID 31160588    Organism Homo sapiens Experiment description Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Authors Sung PS, Huang TF, Hsieh SL. Journal name Nat Commun Publication year 2019 Sample Platelets Sample name Peripheral blood of healthy donors Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Flow cytometry EV-TRACK -