Description for KRAS |
| DNA |
KRAS |
| Species |
Homo sapiens |
KRAS identified in exosomes derived from the following tissue/cell type |
|
Plasma [Extracellular Vesicles]
|
33915956
|
|
Plasma [Extracellular Vesicles]
|
36591510
|
|
Plasma [Nanoscale extracellular Vesicles]
|
31232418
|
|
Plasma [Extracellular Vesicles]
|
31596073
|
|
Plasma [Extracellular Vesicles]
|
33915956
|
|
Pleural effusion [Exosomes]
|
31555514
|
|
Serum [Exosomes]
|
24398677
|
Experiment description of studies that identified KRAS in exosomes |
| 1
|
| Experiment ID | 3576 |
| Identified molecule | dsDNA-mutated |
| Identification method | Whole exosome sequencing |
| PubMed ID |
33915956
|
| Organism | Homo sapiens |
| Experiment description | Exosomes from Plasma of Neuroblastoma Patients Contain Doublestranded DNA Reflecting the Mutational Status of Parental Tumor Cells |
| Authors | Degli Esposti C, Iadarola B, Maestri S, Beltrami C, Lavezzari D, Morini M, De Marco P, Erminio G, Garaventa A, Zara F, Delledonne M, Ognibene M, Pezzolo A. |
| Journal name |
Int J Mol Sci
|
| Publication year | 2021 |
| Sample | Plasma |
| Sample name | Neuroblastoma |
| Molecules identified in the study | dsDNA-mutated |
| Methods used in the study | Whole exosome sequencing |
| EV-TRACK |
-
|
|
|
| 2
|
| Experiment ID | 3556 |
| Identified molecule | dsDNA |
| Identification method | ddPCR |
| PubMed ID |
36591510
|
| Organism | Homo sapiens |
| Experiment description | Detection of circulating KRAS mutant DNA in extracellular vesicles using droplet digital PCR in patients with colon cancer |
| Authors | Choi J, Cho HY, Jeon J, Kim KA, Han YD, Ahn JB, Wortzel I, Lyden D, Kim HS. |
| Journal name |
Front Oncol
|
| Publication year | 2022 |
| Sample | Plasma |
| Sample name | Colon cancer |
| Molecules identified in the study | dsDNA |
| Methods used in the study | ddPCR |
| EV-TRACK |
-
|
|
|
| 3
|
| Experiment ID | 3544 |
| Identified molecule | dsDNA |
| Identification method | ddPCR |
| PubMed ID |
31232418
|
| Organism | Homo sapiens |
| Experiment description | Enrichment of extracellular vesicles with lipid nanoprobe functionalized nanostructured silica |
| Authors | Wan Y, Maurer M, He HZ, Xia YQ, Hao SJ, Zhang WL, Yee NS, Zheng SY. |
| Journal name |
Lab Chip
|
| Publication year | 2019 |
| Sample | Plasma |
| Sample name | Pancreatic cancer |
| Molecules identified in the study | dsDNA |
| Methods used in the study | ddPCR |
| EV-TRACK |
-
|
|
|
| 4
|
| Experiment ID | 3541 |
| Identified molecule | dsDNA |
| Identification method | Whole exosome sequencing |
| PubMed ID |
31596073
|
| Organism | Homo sapiens |
| Experiment description | Isolation and Retrieval of Extracellular Vesicles for Liquid Biopsy of Malignant Ground-Glass Opacity |
| Authors | Mao W, Wen Y, Lei H, Lu R, Wang S, Wang Y, Chen R, Gu Y, Zhu L, Abhange KK, Quinn ZJ, Chen Y, Xue F, Zheng M, Wan Y. |
| Journal name |
Anal Chem
|
| Publication year | 2019 |
| Sample | Plasma |
| Sample name | Lung adenocarcinoma |
| Molecules identified in the study | dsDNA |
| Methods used in the study | Whole exosome sequencing |
| EV-TRACK |
-
|
|
|
| 5
|
| Experiment ID | 3539 |
| Identified molecule | dsDNA |
| Identification method | Whole exosome sequencing |
| PubMed ID |
33915956
|
| Organism | Homo sapiens |
| Experiment description | Exosomes from Plasma of Neuroblastoma Patients Contain Doublestranded DNA Reflecting the Mutational Status of Parental Tumor Cells |
| Authors | Degli Esposti C, Iadarola B, Maestri S, Beltrami C, Lavezzari D, Morini M, De Marco P, Erminio G, Garaventa A, Zara F, Delledonne M, Ognibene M, Pezzolo A. |
| Journal name |
Int J Mol Sci
|
| Publication year | 2021 |
| Sample | Plasma |
| Sample name | Neuroblastoma |
| Molecules identified in the study | dsDNA |
| Methods used in the study | Whole exosome sequencing |
| EV-TRACK |
-
|
|
|
| 6
|
| Experiment ID | 3552 |
| Identified molecule | dsDNA |
| Identification method | Next generation sequencing |
| PubMed ID |
31555514
|
| Organism | Homo sapiens |
| Experiment description | Liquid biopsies using pleural effusion-derived exosomal DNA in advanced lung adenocarcinoma |
| Authors | Song Z, Cai Z, Yan J, Shao YW, Zhang Y. |
| Journal name |
Transl Lung Cancer Res
|
| Publication year | 2019 |
| Sample | Pleural effusion |
| Sample name | Lung adenocarcinoma |
| Molecules identified in the study | dsDNA |
| Methods used in the study | Next generation sequencing |
| EV-TRACK |
-
|
|
|
| 7
|
| Experiment ID | 3555 |
| Identified molecule | dsDNA |
| Identification method | PCR Sanger sequencing Whole genome shotgun sequencing |
| PubMed ID |
24398677
|
| Organism | Homo sapiens |
| Experiment description | Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer |
| Authors | Kahlert C, Melo SA, Protopopov A, Tang J, Seth S, Koch M, Zhang J, Weitz J, Chin L, Futreal A, Kalluri R. |
| Journal name |
J Biol Chem
|
| Publication year | 2014 |
| Sample | Serum |
| Sample name | Pancreatic cancer |
| Molecules identified in the study | dsDNA |
| Methods used in the study | PCR Sanger sequencing Whole genome shotgun sequencing |
| EV-TRACK |
-
|
|
|