Description for EGFR-T790M
DNA	EGFR-T790M
Species	Homo sapiens
EGFR-T790M identified in exosomes derived from the following tissue/cell type
Plasma [Extracellular Vesicles]	31596073
Pleural effusion [Exosomes]	31555514
Pleural effusion [Exosomes]	31608233
Experiment description of studies that identified EGFR-T790M in exosomes
1 Experiment ID 3578 Identified molecule dsDNA-mutated Identification method Whole exosome sequencing PubMed ID 31596073    Organism Homo sapiens Experiment description Isolation and Retrieval of Extracellular Vesicles for Liquid Biopsy of Malignant Ground-Glass Opacity Authors Mao W, Wen Y, Lei H, Lu R, Wang S, Wang Y, Chen R, Gu Y, Zhu L, Abhange KK, Quinn ZJ, Chen Y, Xue F, Zheng M, Wan Y. Journal name Anal Chem Publication year 2019 Sample Plasma Sample name Lung adenocarcinoma Molecules identified in the study dsDNA-mutated Methods used in the study Whole exosome sequencing EV-TRACK -
2 Experiment ID 3582 Identified molecule dsDNA-mutated Identification method Next generation sequencing PubMed ID 31555514    Organism Homo sapiens Experiment description Liquid biopsies using pleural effusion-derived exosomal DNA in advanced lung adenocarcinoma. Authors Song Z, Cai Z, Yan J, Shao YW, Zhang Y. Journal name Transl Lung Cancer Res Publication year 2019 Sample Pleural effusion Sample name Lung adenocarcinoma Molecules identified in the study dsDNA-mutated Methods used in the study Next generation sequencing EV-TRACK -
3 Experiment ID 3575 Identified molecule dsDNA-mutated Identification method qPCR PubMed ID 31608233    Organism Homo sapiens Experiment description Double-Stranded DNA in Exosomes of Malignant Pleural Effusions as a Novel DNA Source for EGFR Mutation Detection in Lung Adenocarcinoma Authors Qu X, Li Q, Yang J, Zhao H, Wang F, Zhang F, Zhang S, Zhang H, Wang R, Wang Q, Wang Q, Li G, Peng X, Zhou X, Hao Y, Zhu J, Xiao W. Journal name Front Oncol Publication year 2019 Sample Pleural effusion Sample name Lung adenocarcinoma Molecules identified in the study dsDNA-mutated Methods used in the study qPCR EV-TRACK -