Gene description for CD86
Gene name	CD86 molecule
Gene symbol	CD86
Other names/aliases	B7-2 B7.2 B70 CD28LG2 LAB72
Species	Homo sapiens
Experiment description of studies that identified CD86 in B cells
1 Experiment ID 16 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 9685355    Organism Homo sapiens Experiment description Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. Authors Escola JM, Kleijmeer MJ, Stoorvogel W, Griffith JM, Yoshie O, Geuze HJ Journal name JBC Publication year 1998 Sample B cells Sample name RN (HLA-DR15+) Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.12-1.18 g/mL Molecules identified in the study Protein Methods used in the study Western blotting Immunoelectron microscopy EV-TRACK -
2 Experiment ID 37 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 10878338    Organism Homo sapiens Experiment description Direct immunosuppressive effects of EBV-encoded latent membrane protein 1. Authors Dukers DF, Meij P, Vervoort MB, Vos W, Scheper RJ, Meijer CJ, Bloemena E, Middeldorp JM Journal name JIMMU Publication year 2000 Sample B cells Sample name JY B95-8 Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
3 Experiment ID 47 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method FACS PubMed ID 17641064    Organism Homo sapiens Experiment description Exosomes with immune modulatory features are present in human breast milk. Authors Admyre C, Johansson SM, Qazi KR, FiléJJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S Journal name JIMMU Publication year 2007 Sample B cells Sample name B cells Isolation/purification methods Differential centrifugation Filtration Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study FACS EV-TRACK -