Gene description for TSG101
Gene name tumor susceptibility 101
Gene symbol TSG101
Other names/aliases TSG10
VPS23
Species Homo sapiens
 Experiment description of studies that identified TSG101 in Serum

1
Experiment ID1805
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36517516   
OrganismHomo sapiens
Experiment descriptionExosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes
AuthorsZhao D, Wu K, Sharma S, Xing F, Wu SY, Tyagi A, Deshpande R, Singh R, Wabitsch M, Mo YY, Watabe K.
Journal name Nat Commun
Publication year2022
SampleSerum
Sample nameBreast cancer patients - African American
Isolation/purification methodsExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qPCR
Small RNA sequencing
EV-TRACK -

2
Experiment ID1806
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36517516   
OrganismHomo sapiens
Experiment descriptionExosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes
AuthorsZhao D, Wu K, Sharma S, Xing F, Wu SY, Tyagi A, Deshpande R, Singh R, Wabitsch M, Mo YY, Watabe K.
Journal name Nat Commun
Publication year2022
SampleSerum
Sample nameBreast cancer patients - African American
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

3
Experiment ID3063
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 33827783   
OrganismHomo sapiens
Experiment descriptionExosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment
AuthorsXie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF.
Journal name Gut
Publication year2022
SampleSerum
Sample nameNormal pancreatic tissue
Isolation/purification methodsTotal Exosome isolation Kit
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

4
Experiment ID3064
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 33827783   
OrganismHomo sapiens
Experiment descriptionExosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment
AuthorsXie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF.
Journal name Gut
Publication year2022
SampleSerum
Sample namePancreatic ductal adenocarcinoma tissue with liver metastasis
Isolation/purification methodsTotal Exosome isolation Kit
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

5
Experiment ID3065
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 33827783   
OrganismHomo sapiens
Experiment descriptionExosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment
AuthorsXie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF.
Journal name Gut
Publication year2022
SampleSerum
Sample namePancreatic ductal adenocarcinoma tissue without liver metastasis
Isolation/purification methodsTotal Exosome isolation Kit
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

6
Experiment ID3068
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 33827783   
OrganismHomo sapiens
Experiment descriptionExosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment
AuthorsXie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF.
Journal name Gut
Publication year2022
SampleSerum
Sample nameHealthy controls
Isolation/purification methodsTotal Exosome isolation Kit
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immuno-EM
EV-TRACK -

7
Experiment ID3069
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 33827783   
OrganismHomo sapiens
Experiment descriptionExosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment
AuthorsXie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF.
Journal name Gut
Publication year2022
SampleSerum
Sample namePancreatic ductal adenocarcinoma patients
Isolation/purification methodsTotal Exosome isolation Kit
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immuno-EM
EV-TRACK -

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