Gene description for TSG101
Gene name	tumor susceptibility 101
Gene symbol	TSG101
Other names/aliases	TSG10 VPS23
Species	Homo sapiens
Experiment description of studies that identified TSG101 in Plasma
1 Experiment ID 1533 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 33589572    Organism Homo sapiens Experiment description Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis Authors Lv X, Lian Y, Liu Z, Xiao J, Zhang D, Yin X. Journal name Aging Publication year 2021 Sample Plasma Sample name Non-small cell lung cancer Isolation/purification methods Centrifugation ExoQuick Kit Flotation density - Molecules identified in the study Protein lncRNA Methods used in the study qRT-PCR Western blotting EV-TRACK -
2 Experiment ID 1534 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 33589572    Organism Homo sapiens Experiment description Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis Authors Lv X, Lian Y, Liu Z, Xiao J, Zhang D, Yin X. Journal name Aging Publication year 2021 Sample Plasma Sample name Healthy Isolation/purification methods Centrifugation ExoQuick Kit Flotation density - Molecules identified in the study Protein lncRNA Methods used in the study qRT-PCR Western blotting EV-TRACK -
3 Experiment ID 1961 Identified molecule protein Extracellular vesicle type Exomeres MISEV EV-like nanoparticles Identification method Western blotting PubMed ID 36417505    Organism Homo sapiens Experiment description A solution to the biophysical fractionation of extracellular vesicles: Acoustic Nanoscale Separation via Wave-pillar Excitation Resonance (ANSWER) Authors Zhang J, Chen C, Becker R, Rufo J, Yang S, Mai J, Zhang P, Gu Y, Wang Z, Ma Z, Xia J, Hao N, Tian Z, Wong DTW, Sadovsky Y, Lee LP, Huang TJ. Journal name Sci Adv Publication year 2022 Sample Plasma Sample name Plasma Isolation/purification methods Acoustic nanoscale separation via wave-pillar excitation resonance (ANSWER) Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
4 Experiment ID 1962 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 36417505    Organism Homo sapiens Experiment description A solution to the biophysical fractionation of extracellular vesicles: Acoustic Nanoscale Separation via Wave-pillar Excitation Resonance (ANSWER) Authors Zhang J, Chen C, Becker R, Rufo J, Yang S, Mai J, Zhang P, Gu Y, Wang Z, Ma Z, Xia J, Hao N, Tian Z, Wong DTW, Sadovsky Y, Lee LP, Huang TJ. Journal name Sci Adv Publication year 2022 Sample Plasma Sample name Plasma Isolation/purification methods Acoustic nanoscale separation via wave-pillar excitation resonance (ANSWER) Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
5 Experiment ID 1974 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35915084    Organism Homo sapiens Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Plasma Sample name Healthy donor Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Flow cytometry ELISA Western bloting EV-TRACK -
6 Experiment ID 1978 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35915084    Organism Homo sapiens Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Plasma Sample name Breast cancer patients Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Flow cytometry ELISA Western bloting EV-TRACK -
7 Experiment ID 2027 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 36455873    Organism Homo sapiens Experiment description Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF Authors Zhao J, Zhang W, Wang S, Li Z, Huang Y, Li L. Journal name Aging Publication year 2022 Sample Plasma Sample name Patients with post-operative cognitive dysfunction (POCD) Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Small RNA sequencing RT-qPCR EV-TRACK -
8 Experiment ID 2028 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 36455873    Organism Homo sapiens Experiment description Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF Authors Zhao J, Zhang W, Wang S, Li Z, Huang Y, Li L. Journal name Aging Publication year 2022 Sample Plasma Sample name Patients without post-operative cognitive dysfunction (non-POCD) Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Small RNA sequencing RT-qPCR EV-TRACK -
9 Experiment ID 2259 Identified molecule Protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35661560    Organism Homo sapiens Experiment description Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Authors Chong MC, Silva A, James PF, Wu SSX, Howitt J. Journal name Aging Cell Publication year 2022 Sample Plasma Sample name Plamsa - Young and unfit Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
10 Experiment ID 2260 Identified molecule Protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35661560    Organism Homo sapiens Experiment description Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Authors Chong MC, Silva A, James PF, Wu SSX, Howitt J. Journal name Aging Cell Publication year 2022 Sample Plasma Sample name Plamsa - Young and unfit Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
11 Experiment ID 2261 Identified molecule Protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35661560    Organism Homo sapiens Experiment description Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Authors Chong MC, Silva A, James PF, Wu SSX, Howitt J. Journal name Aging Cell Publication year 2022 Sample Plasma Sample name Plamsa - Young and fit Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
12 Experiment ID 2262 Identified molecule Protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35661560    Organism Homo sapiens Experiment description Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Authors Chong MC, Silva A, James PF, Wu SSX, Howitt J. Journal name Aging Cell Publication year 2022 Sample Plasma Sample name Plamsa - Young and fit Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
13 Experiment ID 2263 Identified molecule Protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35661560    Organism Homo sapiens Experiment description Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Authors Chong MC, Silva A, James PF, Wu SSX, Howitt J. Journal name Aging Cell Publication year 2022 Sample Plasma Sample name Plamsa - Mature and unfit Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
14 Experiment ID 2264 Identified molecule Protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35661560    Organism Homo sapiens Experiment description Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Authors Chong MC, Silva A, James PF, Wu SSX, Howitt J. Journal name Aging Cell Publication year 2022 Sample Plasma Sample name Plamsa - Mature and unfit Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
15 Experiment ID 2265 Identified molecule Protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35661560    Organism Homo sapiens Experiment description Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Authors Chong MC, Silva A, James PF, Wu SSX, Howitt J. Journal name Aging Cell Publication year 2022 Sample Plasma Sample name Plamsa - Mature and fit Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
16 Experiment ID 2266 Identified molecule Protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35661560    Organism Homo sapiens Experiment description Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Authors Chong MC, Silva A, James PF, Wu SSX, Howitt J. Journal name Aging Cell Publication year 2022 Sample Plasma Sample name Plamsa - Mature and fit Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
17 Experiment ID 2267 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36624553    Organism Homo sapiens Experiment description Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Authors Wang Y, Zhang Y, Li Z, Wei S, Chi X, Yan X, Lv H, Zhao L, Zhao L. Journal name Proteomics Publication year 2023 Sample Plasma Sample name Plasma Isolation/purification methods Filtration Size exclusion chromatography Centrifugal ultrafiltration Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry EV-TRACK -
18 Experiment ID 2268 Identified molecule Protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36624553    Organism Homo sapiens Experiment description Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Authors Wang Y, Zhang Y, Li Z, Wei S, Chi X, Yan X, Lv H, Zhao L, Zhao L. Journal name Proteomics Publication year 2023 Sample Plasma Sample name Plasma - Ion exchange adsorption 12.5 mg Isolation/purification methods Filtration Size exclusion chromatography Ion exchange adsorption Centrifugation Centrifugal ultrafiltration Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry EV-TRACK -
19 Experiment ID 2269 Identified molecule Protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36624553    Organism Homo sapiens Experiment description Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Authors Wang Y, Zhang Y, Li Z, Wei S, Chi X, Yan X, Lv H, Zhao L, Zhao L. Journal name Proteomics Publication year 2023 Sample Plasma Sample name Plasma - Ion exchange adsorption 25 mg Isolation/purification methods Filtration Size exclusion chromatography Ion exchange adsorption Centrifugation Centrifugal ultrafiltration Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry EV-TRACK -
20 Experiment ID 2317 Identified molecule Protein Extracellular vesicle type Extracellular vesicles/Exosomes MISEV EVs Identification method Western blotting PubMed ID 31762962    Organism Homo sapiens Experiment description Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Authors Sundar IK, Li D, Rahman I. Journal name J Extracell Vesicles Publication year 2019 Sample Plasma Sample name Non-smokers Isolation/purification methods ExoQuick Kit Flotation density - Molecules identified in the study Protein small RNA Methods used in the study Western blotting Small RNA sequencing EV-TRACK -
21 Experiment ID 2318 Identified molecule Protein Extracellular vesicle type Extracellular vesicles/Exosomes MISEV EVs Identification method Western blotting PubMed ID 31762962    Organism Homo sapiens Experiment description Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Authors Sundar IK, Li D, Rahman I. Journal name J Extracell Vesicles Publication year 2019 Sample Plasma Sample name Smokers Isolation/purification methods ExoQuick Kit Flotation density - Molecules identified in the study Protein small RNA Methods used in the study Western blotting Small RNA sequencing EV-TRACK -
22 Experiment ID 2319 Identified molecule Protein Extracellular vesicle type Extracellular vesicles/Exosomes MISEV EVs Identification method Western blotting PubMed ID 31762962    Organism Homo sapiens Experiment description Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Authors Sundar IK, Li D, Rahman I. Journal name J Extracell Vesicles Publication year 2019 Sample Plasma Sample name COPD patients Isolation/purification methods ExoQuick Kit Flotation density - Molecules identified in the study Protein small RNA Methods used in the study Western blotting Small RNA sequencing EV-TRACK -
23 Experiment ID 2848 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35058437    Organism Homo sapiens Experiment description Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Authors El-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H. Journal name Nat Commun Publication year 2022 Sample Plasma Sample name NWL-001 - Lung cancer patient Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry EV-TRACK -
24 Experiment ID 2850 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35058437    Organism Homo sapiens Experiment description Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Authors El-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H. Journal name Nat Commun Publication year 2022 Sample Plasma Sample name CSB-012 - COVID-19 patient - convalescent phase Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry EV-TRACK -
25 Experiment ID 2912 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 26061593    Organism Homo sapiens Experiment description Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Authors Sagar G, Sah RP, Javeed N, Dutta SK, Smyrk TC, Lau JS, Giorgadze N, Tchkonia T, Kirkland JL, Chari ST, Mukhopadhyay D. Journal name Gut Publication year 2017 Sample Plasma Sample name Non-pancreatic cancer control Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
26 Experiment ID 2913 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 26061593    Organism Homo sapiens Experiment description Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Authors Sagar G, Sah RP, Javeed N, Dutta SK, Smyrk TC, Lau JS, Giorgadze N, Tchkonia T, Kirkland JL, Chari ST, Mukhopadhyay D. Journal name Gut Publication year 2017 Sample Plasma Sample name Pancreatic cancer patients Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
27 Experiment ID 2991 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 30089911    Organism Homo sapiens Experiment description Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Authors Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. Journal name Nature Publication year 2018 Sample Plasma Sample name Healthy donors Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting ELISA EV-TRACK -
28 Experiment ID 2992 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 30089911    Organism Homo sapiens Experiment description Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Authors Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. Journal name Nature Publication year 2018 Sample Plasma Sample name Melanoma stage IV patients Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting ELISA EV-TRACK -
29 Experiment ID 2995 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 30089911    Organism Homo sapiens Experiment description Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Authors Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. Journal name Nature Publication year 2018 Sample Plasma Sample name Melanoma stage IV patients - Fraction 7 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density 1.44 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
30 Experiment ID 2996 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 30089911    Organism Homo sapiens Experiment description Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Authors Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. Journal name Nature Publication year 2018 Sample Plasma Sample name Melanoma stage IV patients - Fraction 8 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density 1.56 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
31 Experiment ID 2997 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 30089911    Organism Homo sapiens Experiment description Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Authors Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. Journal name Nature Publication year 2018 Sample Plasma Sample name Melanoma stage IV patients - Fraction 9 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density 1.178 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
32 Experiment ID 2998 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 30089911    Organism Homo sapiens Experiment description Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Authors Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. Journal name Nature Publication year 2018 Sample Plasma Sample name Melanoma stage IV patients - Fraction 10 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density 1.193 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
33 Experiment ID 3086 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Plasma Sample name Healthy donors Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
34 Experiment ID 3087 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Plasma Sample name Hepatocellular carcinoma patients Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM EV-TRACK -
35 Experiment ID 3139 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 34497265    Organism Homo sapiens Experiment description Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Authors Ma Z, Wei K, Yang F, Guo Z, Pan C, He Y, Wang J, Li Z, Chen L, Chen Y, Xia Y. Journal name Cell Death Dis Publication year 2021 Sample Plasma Sample name Non-small cell lung carcinoma patients Isolation/purification methods ExoQuick Kit Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Microarray EV-TRACK -
36 Experiment ID 3140 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 34497265    Organism Homo sapiens Experiment description Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Authors Ma Z, Wei K, Yang F, Guo Z, Pan C, He Y, Wang J, Li Z, Chen L, Chen Y, Xia Y. Journal name Cell Death Dis Publication year 2021 Sample Plasma Sample name Healthy controls Isolation/purification methods ExoQuick Kit Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Microarray EV-TRACK -
37 Experiment ID 3197 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 34690112    Organism Homo sapiens Experiment description Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling Authors Lai Y, Dong L, Jin H, Li H, Sun M, Li J. Journal name Aging Publication year 2021 Sample Plasma Sample name Healthy donors Isolation/purification methods ExoQuick Kit Flotation density - Molecules identified in the study Protein lncRNA Methods used in the study Western blotting lncRNA profiling qPCR EV-TRACK -
38 Experiment ID 3198 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 34690112    Organism Homo sapiens Experiment description Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling Authors Lai Y, Dong L, Jin H, Li H, Sun M, Li J. Journal name Aging Publication year 2021 Sample Plasma Sample name Ovarian cancer patients Isolation/purification methods ExoQuick Kit Flotation density - Molecules identified in the study Protein lncRNA Methods used in the study Western blotting lncRNA profiling qPCR EV-TRACK -
39 Experiment ID 2399 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34355211    Organism Homo sapiens Experiment description A size-exclusion-based approach for purifying extracellular vesicles from human plasma Authors Vanderboom PM, Dasari S, Ruegsegger GN, Pataky MW, Lucien F, Heppelmann CJ, Lanza IR, Nair KS. Journal name Cell Rep Methods Publication year 2021 Sample Plasma Sample name Plasma Isolation/purification methods Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
40 Experiment ID 2431 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 29320704    Organism Homo sapiens Experiment description Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Authors Whitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA. Journal name Cell Metab Publication year 2018 Sample Plasma Sample name Plasma - 20K pellet Isolation/purification methods Centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
41 Experiment ID 2432 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 29320704    Organism Homo sapiens Experiment description Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Authors Whitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA. Journal name Cell Metab Publication year 2018 Sample Plasma Sample name Plasma - 100K pellet Isolation/purification methods Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
42 Experiment ID 2436 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 29320704    Organism Homo sapiens Experiment description Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Authors Whitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA. Journal name Cell Metab Publication year 2018 Sample Plasma Sample name Plasma Isolation/purification methods Centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -