Gene description for TSG101
Gene name tumor susceptibility 101
Gene symbol TSG101
Other names/aliases TSG10
VPS23
Species Homo sapiens
 Experiment description of studies that identified TSG101 in Fibroblasts

1
Experiment ID1803
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35917363   
OrganismHomo sapiens
Experiment descriptionCD9 mediates the uptake of extracellular vesicles from cancer-associated fibroblasts that promote pancreatic cancer cell aggressiveness
AuthorsNigri J, Leca J, Tubiana SS, Finetti P, Guillaumond F, Martinez S, Lac S, Iovanna JL, Audebert S, Camoin L, Vasseur S, Bertucci F, Tomasini R.
Journal name Sci Signal
Publication year2022
SampleFibroblasts
Sample nameCAF - Pancreatic ductal adenocarcinoma
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectometry
EV-TRACK -

2
Experiment ID1804
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35917363   
OrganismHomo sapiens
Experiment descriptionCD9 mediates the uptake of extracellular vesicles from cancer-associated fibroblasts that promote pancreatic cancer cell aggressiveness
AuthorsNigri J, Leca J, Tubiana SS, Finetti P, Guillaumond F, Martinez S, Lac S, Iovanna JL, Audebert S, Camoin L, Vasseur S, Bertucci F, Tomasini R.
Journal name Sci Signal
Publication year2022
SampleFibroblasts
Sample nameCAF - Pancreatic ductal adenocarcinoma
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectometry
EV-TRACK -

3
Experiment ID2331
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 36635419   
OrganismHomo sapiens
Experiment descriptionIntradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy
AuthorsYou Y, Tian Y, Yang Z, Shi J, Kwak KJ, Tong Y, Estania AP, Cao J, Hsu WH, Liu Y, Chiang CL, Schrank BR, Huntoon K, Lee D, Li Z, Zhao Y, Zhang H, Gallup TD, Ha J, Dong S, Li X, Wang Y, Lu WJ, Bahrani E, Lee LJ, Teng L, Jiang W, Lan F, Kim BYS, Lee AS.
Journal name Nat Biomed Eng
Publication year2023
SampleFibroblasts
Sample nameNormal human dermal fibroblasts
Isolation/purification methodsCentrifugal ultrafiltration
Immunoaffinity capture
Flotation density-
Molecules identified in the studyProtein
mRNA
Methods used in the studyRT-qPCR
Western blotting
EV-TRACK -

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