Gene description for TP53
Gene name	tumor protein p53
Gene symbol	TP53
Other names/aliases	BCC7 BMFS5 LFS1 P53 TRP53
Species	Homo sapiens
Experiment description of studies that identified TP53 in Breast cancer cells
1 Experiment ID 1230 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Mass spectrometry PubMed ID 25503107    Organism Homo sapiens Experiment description Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN. Authors Menck K, Scharf C, Bleckmann A, Dyck L, Rost U, Wenzel D, Dhople VM, Siam L, Pukrop T, Binder C, Klemm F. Journal name J Mol Cell Biol. Publication year 2015 Sample Breast cancer cells Sample name MCF-7 Isolation/purification methods Ultracentrifugation Filtration Density gradient centrifugation Flotation density 1.13-1.22 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140270: EV-METRIC:0%, 33%, 33%
2 Experiment ID 1231 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Mass spectrometry PubMed ID 25503107    Organism Homo sapiens Experiment description Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN. Authors Menck K, Scharf C, Bleckmann A, Dyck L, Rost U, Wenzel D, Dhople VM, Siam L, Pukrop T, Binder C, Klemm F. Journal name J Mol Cell Biol. Publication year 2015 Sample Breast cancer cells Sample name SK-BR-3 Isolation/purification methods Ultracentrifugation Filtration Density gradient centrifugation Flotation density 1.13-1.22 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140270: EV-METRIC:0%, 33%, 33%
3 Experiment ID 1678 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Mass spectrometry PubMed ID 34108659    Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. Journal name Nat Cell Biol Publication year 2021 Sample Breast cancer cells Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry EV-TRACK -
4 Experiment ID 1679 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Mass spectrometry PubMed ID 34108659    Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. Journal name Nat Cell Biol Publication year 2021 Sample Breast cancer cells Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -