Gene description for PTGIS
Gene name	prostaglandin I2 synthase
Gene symbol	PTGIS
Other names/aliases	CYP8 CYP8A1 PGIS PTGI
Species	Homo sapiens
Experiment description of studies that identified PTGIS in Valvular interstitial cells
1 Experiment ID 1353 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 32938681    Organism Homo sapiens Experiment description Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis Authors Rogers MA, Buffolo F, Schlotter F, Atkins SK, Lee LH, Halu A, Blaser MC, Tsolaki E, Higashi H, Luther K, Daaboul G, Bouten CVC, Body SC, Singh SA, Bertazzo S, Libby P, Aikawa M, Aikawa E. Journal name Sci Adv Publication year 2020 Sample Valvular interstitial cells Sample name Aortic valve-derived primary valvular interstial cells Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
2 Experiment ID 1354 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 32938681    Organism Homo sapiens Experiment description Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis Authors Rogers MA, Buffolo F, Schlotter F, Atkins SK, Lee LH, Halu A, Blaser MC, Tsolaki E, Higashi H, Luther K, Daaboul G, Bouten CVC, Body SC, Singh SA, Bertazzo S, Libby P, Aikawa M, Aikawa E. Journal name Sci Adv Publication year 2020 Sample Valvular interstitial cells Sample name Aortic valve-derived primary valvular interstial cells Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -