Gene description for SERPINC1
Gene name serpin family C member 1
Gene symbol SERPINC1
Other names/aliases AT3
AT3D
ATIII
ATIII-R2
ATIII-T1
ATIII-T2
THPH7
Species Homo sapiens
 Experiment description of studies that identified SERPINC1 in Urine

1
Experiment ID437
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22106071   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).
AuthorsWang Z, Hill S, Luther JM, Hachey DL, Schey KL.
Journal name Proteomics
Publication year2012
SampleUrine
Sample nameNormal donors-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120168: EV-METRIC:14%

2
Experiment ID498
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 23376485   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of podocyte exosome-enriched fraction from normal human urine.
AuthorsPrunotto M, Farina A, Lane L, Pernin A, Schifferli J, Hochstrasser DF, Lescuyer P, Moll S.
Journal name J Proteomics
Publication year2013
SampleUrine
Sample nameNormal-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130051: EV-METRIC:38%

3
Experiment ID507
Identified moleculeprotein
Extracellular vesicle typeExosomes/Nanovesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 23511837   
OrganismHomo sapiens
Experiment descriptionDifferential protein profiling of renal cell carcinoma urinary exosomes.
AuthorsRaimondo F, Morosi L, Corbetta S, Chinello C, Brambilla P, Della Mina P, Villa A, Albo G, Battaglia C, Bosari S, Magni F, Pitto M.
Journal name Mol Biosyst
Publication year2013
SampleUrine
Sample nameNormal-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130016: EV-METRIC:44%

4
Experiment ID508
Identified moleculeprotein
Extracellular vesicle typeExosomes/Nanovesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 23511837   
OrganismHomo sapiens
Experiment descriptionDifferential protein profiling of renal cell carcinoma urinary exosomes.
AuthorsRaimondo F, Morosi L, Corbetta S, Chinello C, Brambilla P, Della Mina P, Villa A, Albo G, Battaglia C, Bosari S, Magni F, Pitto M.
Journal name Mol Biosyst
Publication year2013
SampleUrine
Sample nameRenal cell carcinoma patient-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130016: EV-METRIC:44%

5
Experiment ID512
Identified moleculeprotein
Extracellular vesicle typeExosomes/Microvesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 23533145   
OrganismHomo sapiens
Experiment descriptionIn-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
AuthorsPrincipe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR.
Journal name Proteomics
Publication year2013
SampleUrine
Sample nameLow-grade prostate cancer patient-Expressed prostatic secretions in urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130224: EV-METRIC:14%

6
Experiment ID513
Identified moleculeprotein
Extracellular vesicle typeExosomes/Microvesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 23533145   
OrganismHomo sapiens
Experiment descriptionIn-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
AuthorsPrincipe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR.
Journal name Proteomics
Publication year2013
SampleUrine
Sample nameNormal-Expressed prostatic secretions in urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130224: EV-METRIC:14%

7
Experiment ID1027
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24211404   
OrganismHomo sapiens
Experiment descriptionDiabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis.
AuthorsZubiri I, Posada-Ayala M, Sanz-Maroto A, Calvo E, Martin-Lorenzo M, Gonzalez-Calero L, de la Cuesta F, Lopez JA, Fernandez-Fernandez B, Ortiz A, Vivanco F, Alvarez-Llamas G.
Journal name J Proteomics.
Publication year2014
SampleUrine
Sample nameUrine - Diabetic nephropathy (DN) patients
Isolation/purification methodsUltracentrifugation
ExoQuick
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140245: EV-METRIC:22%, 25%, 22%

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