Gene description for ITGAV
Gene name integrin subunit alpha V
Gene symbol ITGAV
Other names/aliases CD51
MSK8
VNRA
VTNR
Species Homo sapiens
 Experiment description of studies that identified ITGAV in Plasma

1
Experiment ID224
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
Confocal microscopy
PubMed ID 10393703   
OrganismHomo sapiens
Experiment descriptionIn vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant
AuthorsCombes V, Simon AC, Grau GE, Arnoux D, Camoin L, Sabatier F, Mutin M, Sanmarco M, Sampol J, Dignat-George F
Journal name J Clin Invest
Publication year1999
SamplePlasma
Sample namePlasma - Normal
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyConfocal microscopy
FACS
EV-TRACK -

2
Experiment ID225
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 10393703   
OrganismHomo sapiens
Experiment descriptionIn vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant
AuthorsCombes V, Simon AC, Grau GE, Arnoux D, Camoin L, Sabatier F, Mutin M, Sanmarco M, Sampol J, Dignat-George F
Journal name J Clin Invest
Publication year1999
SamplePlasma
Sample namePlasma - Lupus anticoagulant
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
EV-TRACK -

3
Experiment ID288
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12196479   
OrganismHomo sapiens
Experiment descriptionType 1 and type 2 diabetic patients display different patterns of cellular microparticles
AuthorsSabatier F, Darmon P, Hugel B, Combes V, Sanmarco M, Velut JG, Arnoux D, Charpiot P, Freyssinet JM, Oliver C, Sampol J, Dignat-George F
Journal name Diabetes
Publication year2002
SamplePlasma
Sample namePlasma - Healthy donors
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Lipids
Methods used in the studyFACS
Annexin V-FITC
EV-TRACK -

4
Experiment ID289
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12196479   
OrganismHomo sapiens
Experiment descriptionType 1 and type 2 diabetic patients display different patterns of cellular microparticles
AuthorsSabatier F, Darmon P, Hugel B, Combes V, Sanmarco M, Velut JG, Arnoux D, Charpiot P, Freyssinet JM, Oliver C, Sampol J, Dignat-George F
Journal name Diabetes
Publication year2002
SamplePlasma
Sample namePlasma - Type 1 diabetes
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Lipids
Methods used in the studyFACS
Annexin V-FITC
EV-TRACK -

5
Experiment ID290
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12196479   
OrganismHomo sapiens
Experiment descriptionType 1 and type 2 diabetic patients display different patterns of cellular microparticles
AuthorsSabatier F, Darmon P, Hugel B, Combes V, Sanmarco M, Velut JG, Arnoux D, Charpiot P, Freyssinet JM, Oliver C, Sampol J, Dignat-George F
Journal name Diabetes
Publication year2002
SamplePlasma
Sample namePlasma - Type 2 diabetes
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Lipids
Methods used in the studyFACS
Annexin V-FITC
EV-TRACK -

6
Experiment ID296
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12796750   
OrganismHomo sapiens
Experiment descriptionHigh levels of circulating endothelial microparticles in patients with acute coronary syndromes
AuthorsBernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS
Journal name Am Heart J
Publication year2003
SamplePlasma
Sample namePlasma - Normal
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
EV-TRACK -

7
Experiment ID297
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12796750   
OrganismHomo sapiens
Experiment descriptionHigh levels of circulating endothelial microparticles in patients with acute coronary syndromes
AuthorsBernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS
Journal name Am Heart J
Publication year2003
SamplePlasma
Sample namePlasma - Acute coronary syndrome
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
EV-TRACK -

8
Experiment ID298
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12796750   
OrganismHomo sapiens
Experiment descriptionHigh levels of circulating endothelial microparticles in patients with acute coronary syndromes
AuthorsBernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS
Journal name Am Heart J
Publication year2003
SamplePlasma
Sample namePlasma - Coronary artery disease
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
EV-TRACK -

9
Experiment ID299
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12796750   
OrganismHomo sapiens
Experiment descriptionHigh levels of circulating endothelial microparticles in patients with acute coronary syndromes
AuthorsBernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS
Journal name Am Heart J
Publication year2003
SamplePlasma
Sample namePlasma - Myocardial infarction
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
EV-TRACK -

10
Experiment ID284
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12796750   
OrganismHomo sapiens
Experiment descriptionHigh levels of circulating endothelial microparticles in patients with acute coronary syndromes
AuthorsBernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS
Journal name Am Heart J
Publication year2003
SamplePlasma
Sample namePlasma - Stable angina
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
EV-TRACK -

11
Experiment ID285
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12796750   
OrganismHomo sapiens
Experiment descriptionHigh levels of circulating endothelial microparticles in patients with acute coronary syndromes
AuthorsBernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS
Journal name Am Heart J
Publication year2003
SamplePlasma
Sample namePlasma - Unstable angina
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
EV-TRACK -

12
Experiment ID863
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22046311   
OrganismMus musculus
Experiment descriptionExosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections
AuthorsMartin-Jaular L, Nakayasu ES, Ferrer M, Almeida IC, Del Portillo HA.
Journal name PLoS One
Publication year2011
SamplePlasma
Sample namePeripheral blood plasma - P. yoelii 17X infected
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
Mass spectrometry
EV-TRACK EV110102: EV-METRIC:25%, 25%

13
Experiment ID2329
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 32487994   
OrganismHomo sapiens
Experiment descriptionPlasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence
AuthorsToda H, Diaz-Varela M, Segui-Barber J, Roobsoong W, Baro B, Garcia-Silva S, Galiano A, Gualdrón-López M, Almeida ACG, Brito MAM, de Melo GC, Aparici-Herraiz I, Castro-Cavadía C, Monteiro WM, Borràs E, Sabidó E, Almeida IC, Chojnacki J, Martinez-Picado J, Calvo M, Armengol P, Carmona-Fonseca J, Yasnot MF, Lauzurica R, Marcilla A, Peinado H, Galinski MR, Lacerda MVG, Sattabongkot J, Fernandez-Becerra C, Del Portillo HA.
Journal name Nat Commun
Publication year2020
SamplePlasma
Sample nameHealthy donors
Isolation/purification methodsCentrifugation
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
Flow cytometry
EV-TRACK -

14
Experiment ID2330
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 32487994   
OrganismHomo sapiens
Experiment descriptionPlasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence
AuthorsToda H, Diaz-Varela M, Segui-Barber J, Roobsoong W, Baro B, Garcia-Silva S, Galiano A, Gualdrón-López M, Almeida ACG, Brito MAM, de Melo GC, Aparici-Herraiz I, Castro-Cavadía C, Monteiro WM, Borràs E, Sabidó E, Almeida IC, Chojnacki J, Martinez-Picado J, Calvo M, Armengol P, Carmona-Fonseca J, Yasnot MF, Lauzurica R, Marcilla A, Peinado H, Galinski MR, Lacerda MVG, Sattabongkot J, Fernandez-Becerra C, Del Portillo HA.
Journal name Nat Commun
Publication year2020
SamplePlasma
Sample namePlasmodium vivax (Malaria) patients
Isolation/purification methodsCentrifugation
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
Flow cytometry
EV-TRACK -

15
Experiment ID3087
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Immuno-EM
PubMed ID 36631249   
OrganismHomo sapiens
Experiment descriptionS100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos
AuthorsWang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO.
Journal name Gut
Publication year2023
SamplePlasma
Sample nameHepatocellular carcinoma patients
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immuno-EM
EV-TRACK -

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