Gene description for HLA-E
Gene name	major histocompatibility complex, class I, E
Gene symbol	HLA-E
Other names/aliases	HLA-6.2 QA1
Species	Homo sapiens
Experiment description of studies that identified HLA-E in Melanoma cells
1 Experiment ID 24 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 11231627    Organism Homo sapiens Experiment description Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Authors Wolfers J, Lozier A, Raposo G, Regnault A, Thé C, Masurier C, Flament C, Pouzieux S, Faure F, Tursz T, Angevin E, Amigorena S, Zitvogel L. Journal name NM Publication year 2001 Sample Melanoma cells Sample name Fon Mel-888 Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.14 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
2 Experiment ID 617 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name LOX IMVI Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -