Gene description for HLA-B
Gene name	major histocompatibility complex, class I, B
Gene symbol	HLA-B
Other names/aliases	AS B-4901 HLAB
Species	Homo sapiens
Experiment description of studies that identified HLA-B in Serum
1 Experiment ID 201 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Western blotting PubMed ID 21606166    Organism Homo sapiens Experiment description Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta2 Authors Szczepanski MJ, Szajnik M, Welsh A, Whiteside TL, Boyiadzis M Journal name Haematologica Publication year 2011 Sample Serum Sample name Serum - Acute myeloid leukemia Isolation/purification methods Size exclusion chromatography Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting FACS EV-TRACK EV110116: EV-METRIC:11%
2 Experiment ID 200 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Western blotting PubMed ID 21606166    Organism Homo sapiens Experiment description Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta1 Authors Szczepanski MJ, Szajnik M, Welsh A, Whiteside TL, Boyiadzis M Journal name Haematologica Publication year 2011 Sample Serum Sample name Serum - Normal Isolation/purification methods Size exclusion chromatography Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting FACS EV-TRACK EV110116: EV-METRIC:11%
3 Experiment ID 971 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 22808001    Organism Homo sapiens Experiment description Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Authors Musante L, Saraswat M, Duriez E, Byrne B, Ravidà, Domon B, Holthofer H. Journal name PLoS One Publication year 2012 Sample Serum Sample name Serum -Tuberculosis patient 1 Isolation/purification methods Filtration ExoQuick Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120006: EV-METRIC:56%
4 Experiment ID 976 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 22808001    Organism Homo sapiens Experiment description Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Authors Musante L, Saraswat M, Duriez E, Byrne B, Ravidà, Domon B, Holthofer H. Journal name PLoS One Publication year 2012 Sample Serum Sample name Serum -Tuberculosis patient 6 Isolation/purification methods Filtration ExoQuick Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120006: EV-METRIC:56%
5 Experiment ID 2007 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Flow cytometry PubMed ID 35979935    Organism Homo sapiens Experiment description Serum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients Authors Tertel T, Tomić S, Đokić J, Radojević D, Stevanović D, Ilić N, Giebel B, Kosanović M. Journal name J Extracell Vesicles Publication year 2022 Sample Serum Sample name Healthy donors Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Flow cytometry EV-TRACK -
6 Experiment ID 2008 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Flow cytometry PubMed ID 35979935    Organism Homo sapiens Experiment description Serum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients Authors Tertel T, Tomić S, Đokić J, Radojević D, Stevanović D, Ilić N, Giebel B, Kosanović M. Journal name J Extracell Vesicles Publication year 2022 Sample Serum Sample name Severe COVID-19 patients Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Flow cytometry EV-TRACK -
7 Experiment ID 2009 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Flow cytometry PubMed ID 35979935    Organism Homo sapiens Experiment description Serum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients Authors Tertel T, Tomić S, Đokić J, Radojević D, Stevanović D, Ilić N, Giebel B, Kosanović M. Journal name J Extracell Vesicles Publication year 2022 Sample Serum Sample name Mild COVID-19 patients Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Flow cytometry EV-TRACK -