Gene description for GZMB |
| Gene name |
granzyme B |
| Gene symbol |
GZMB |
| Other names/aliases |
C11 CCPI CGL-1 CGL1 CSP-B CSPB CTLA1 CTSGL1 HLP SECT |
| Species |
Homo sapiens |
Experiment description of studies that identified GZMB in Prostate cancer cells |
| 1
|
| Experiment ID | 634 |
| Identified molecule | protein
|
| Extracellular vesicle type | Extracellular vesicles |
| MISEV | EVs |
| Identification method | Mass spectrometry [LTQ]
|
| PubMed ID |
27894104
|
| Organism | Homo sapiens |
| Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
| Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
| Journal name |
Oncotarget
|
| Publication year | 2016 |
| Sample | Prostate cancer cells |
| Sample name | PC-3 |
| Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Mass spectrometry [LTQ] |
| EV-TRACK |
-
|
|
|
| 2
|
| Experiment ID | 2293 |
| Identified molecule | Protein
|
| Extracellular vesicle type | Extracellular vesicles |
| MISEV | Small EVs |
| Identification method | ELISA
|
| PubMed ID |
30891164
|
| Organism | Homo sapiens |
| Experiment description | Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells |
| Authors | Wu CH, Li J, Li L, Sun J, Fabbri M, Wayne AS, Seeger RC, Jong AY. |
| Journal name |
J Extracell Vesicles
|
| Publication year | 2019 |
| Sample | Prostate cancer cells |
| Sample name | DU145 |
| Isolation/purification methods | Polyethylene glycol-based precipitation Centrifugation Dialysis |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | ELISA |
| EV-TRACK |
-
|
|
|