Gene description for ERBB2
Gene name	erb-b2 receptor tyrosine kinase 2
Gene symbol	ERBB2
Other names/aliases	CD340 HER-2 HER-2/neu HER2 MLN 19 MLN-19 NEU NGL TKR1 VSCN2 c-ERB-2 c-ERB2 p185(erbB2)
Species	Homo sapiens
Experiment description of studies that identified ERBB2 in Serum
1 Experiment ID 217 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method ELISA Dot blot PubMed ID 21293856    Organism Homo sapiens Experiment description Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Authors Battke C, Ruiss R, Welsch U, Wimberger P, Lang S, Jochum S, Zeidler R Journal name Cancer Immunol Immunother Publication year 2011 Sample Serum Sample name Serum - Breast cancer Isolation/purification methods Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.17 g/mL Molecules identified in the study Protein Methods used in the study ELISA Dot blot EV-TRACK EV110080: EV-METRIC:14%, 14%, 38%
2 Experiment ID 971 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 22808001    Organism Homo sapiens Experiment description Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Authors Musante L, Saraswat M, Duriez E, Byrne B, Ravidà, Domon B, Holthofer H. Journal name PLoS One Publication year 2012 Sample Serum Sample name Serum -Tuberculosis patient 1 Isolation/purification methods Filtration ExoQuick Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120006: EV-METRIC:56%