Browse results for content type: mirna |
Vesiclepedia ID | PubMed ID | Species | Experiment description | Sample | Identifications | Isolation methods | Vesicle type | MISEV | |
1 | Vesiclepedia_1795 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Neuroblastoma cells | miRNA | Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
2 | Vesiclepedia_1503 | 33953168 | Homo sapiens | Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation | Serum |
Protein miRNA |
ExoQuick Kit | Extracellular vesicles | Small EVs |
3 | Vesiclepedia_1791 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Neuroblastoma cells | miRNA | Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
4 | Vesiclepedia_2316 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | T cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
5 | Vesiclepedia_3248 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
6 | Vesiclepedia_1034 | 29887978 | Homo sapiens | Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. | Serum |
Protein miRNA |
qEV size-exclusion column | Extracellular vesicles | EVs |
7 | Vesiclepedia_84 | 20949044 | Homo sapiens | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line | Lung cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
8 | Vesiclepedia_3235 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
9 | Vesiclepedia_2347 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
10 | Vesiclepedia_2312 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | B cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
11 | Vesiclepedia_463 | 22849433 | Homo sapiens | Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types. | Embryonic kidney cells | miRNA | - | Extracellular vesicles | EVs |
12 | Vesiclepedia_3236 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
13 | Vesiclepedia_3050 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Monocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
14 | Vesiclepedia_1342 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | Muscle | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
15 | Vesiclepedia_1491 | 32024826 | Homo sapiens | Liver governs adipose remodelling via extracellular vesicles in response to lipid overload | Plasma | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
16 | Vesiclepedia_2279 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma | miRNA | Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
17 | Vesiclepedia_2579 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
18 | Vesiclepedia_1163 | 29904572 | Bos taurus | A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. | Bovine milk |
Protein miRNA |
Differential centrifugation Density gradient centrifugation |
Extracellular vesicles | EVs |
19 | Vesiclepedia_530 | 23803555 | Bos taurus | Epididymosomes Convey Different Repertoires of MicroRNAs Throughout the Bovine Epididymis. | Epithelial cells | miRNA | - | Membrane vesicles | EVs |
20 | Vesiclepedia_1478 | 32024826 | Mus musculus | Liver governs adipose remodelling via extracellular vesicles in response to lipid overload | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
21 | Vesiclepedia_2590 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
22 | Vesiclepedia_324 | 20079801 | Mus musculus | Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription | Lung cells |
Protein miRNA |
Differential centrifugation FACS |
Microvesicles | EVs |
23 | Vesiclepedia_1436 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
24 | Vesiclepedia_2740 | 35513391 | Homo sapiens | Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1 | Posterior longitudinal ligament | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Small extracellular vesicles | Small EVs |
25 | Vesiclepedia_3051 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Plasma | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
26 | Vesiclepedia_207 | 21435393 | Rattus norvegicus | Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis | Adipocytes |
mRNA miRNA |
Differential centrifugation Sucrose density gradient Size exclusion chromatography |
Microvesicles | EVs |
27 | Vesiclepedia_2471 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
28 | Vesiclepedia_1169 | 29907695 | Mus musculus | Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. | Melanoma cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | EVs |
29 | Vesiclepedia_1449 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Plasma | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
30 | Vesiclepedia_83 | 20949044 | Homo sapiens | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line | Lung cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
31 | Vesiclepedia_1180 | 29854963 | Homo sapiens | Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. | Urine | miRNA | qEV size-exclusion column | Extracellular vesicles | EVs |
32 | Vesiclepedia_1347 | 33009394 | Homo sapiens | Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p | Platelets | miRNA | Ficoll-Hypaque density gradient centrifugation Differential centrifugation Filtration |
Platelet-derived microparticles | EV-like nanoparticles |
33 | Vesiclepedia_2751 | 35173168 | Homo sapiens | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
34 | Vesiclepedia_1898 | 36260670 | Mus musculus | Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice | Plasma | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
35 | Vesiclepedia_516 | 23539611 | Homo sapiens | microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy. | Seminal fluid | miRNA | - | Microvesicles | EVs |
36 | Vesiclepedia_2461 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Serum | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
37 | Vesiclepedia_2344 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
38 | Vesiclepedia_1174 | 29881354 | Rattus norvegicus | Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content. | Serum |
Protein miRNA |
ExoQuick | Extracellular vesicles | EVs |
39 | Vesiclepedia_2589 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
40 | Vesiclepedia_3242 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
41 | Vesiclepedia_1237 | 25421927 | Heligmosomoides polygyrus | Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. | Heligmosomoides polygyrus |
miRNA Protein |
Filtration Ultracentrifugation |
Exosomes | EVs |
42 | Vesiclepedia_2822 | 34168137 | Bos taurus | Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis | Bovine milk |
Protein mRNA miRNA tRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
43 | Vesiclepedia_1078 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | miRNA | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
44 | Vesiclepedia_689 | 28170197 | Homo sapiens | Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 | Adipose-derived mesenchymal stem cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
45 | Vesiclepedia_2443 | 34489604 | Mus musculus | Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 | Hepatocytes |
Protein miRNA |
Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
46 | Vesiclepedia_2307 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | Monocytes | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
47 | Vesiclepedia_1032 | 29887978 | Homo sapiens | Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. | Serum |
Protein miRNA |
exoEasy columns | Extracellular vesicles | EVs |
48 | Vesiclepedia_2588 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
49 | Vesiclepedia_2528 | 34315885 | Mus musculus | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease | Kidney epithelial cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
50 | Vesiclepedia_3461 | 31451800 | Homo sapiens | Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories | Cardiosphere-derived cells | miRNA | Filtration Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
51 | Vesiclepedia_2336 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
52 | Vesiclepedia_1833 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
53 | Vesiclepedia_1519 | 33953168 | Homo sapiens | Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation | Mast cells | miRNA | ExoQuick Kit | Extracellular vesicles | Small EVs |
54 | Vesiclepedia_3156 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
55 | Vesiclepedia_2314 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | T cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
56 | Vesiclepedia_2525 | 34315885 | Mus musculus | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease | Embryonic kidney cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
57 | Vesiclepedia_1171 | 29881354 | Rattus norvegicus | Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content. | Serum |
Protein miRNA |
ExoQuick | Extracellular vesicles | EVs |
58 | Vesiclepedia_3052 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Plasma | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
59 | Vesiclepedia_1814 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Serum | miRNA | ExoQuick Kit | Exosomes | Small EVs |
60 | Vesiclepedia_2447 | 34489604 | Mus musculus | Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 | Hepatocytes | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
61 | Vesiclepedia_1514 | 33953168 | Homo sapiens | Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation | Serum | miRNA | ExoQuick Kit | Extracellular vesicles | Small EVs |
62 | Vesiclepedia_3046 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Plasma |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
63 | Vesiclepedia_2335 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
64 | Vesiclepedia_2736 | 35545056 | Mus musculus | MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis | Bone marrow cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
65 | Vesiclepedia_3053 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Plasma | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
66 | Vesiclepedia_1922 | 36253358 | Mus musculus | Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM | Mesenchymal stem cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
67 | Vesiclepedia_2453 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells |
Protein miRNA |
Centrifugation Ultracentrifugation |
Microvesicles | Large EVs |
68 | Vesiclepedia_2790 | 35304471 | Mus musculus | Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox | Liver | miRNA | Differential centrifugation Filtration Ultracentrifugation Centrifugal ultrafiltration OptiPrep density gradient centrifugation |
Extracellular vesicles | Small EVs |
69 | Vesiclepedia_2302 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | Monocytes | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
70 | Vesiclepedia_2458 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Ultracentrifugation |
Microvesicles | Large EVs |
71 | Vesiclepedia_3240 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
72 | Vesiclepedia_1437 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
73 | Vesiclepedia_1166 | 29904572 | Bos taurus | A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. | Bovine milk |
Protein miRNA |
Differential centrifugation Density gradient centrifugation |
Extracellular vesicles | EVs |
74 | Vesiclepedia_1488 | 32024826 | Mus musculus | Liver governs adipose remodelling via extracellular vesicles in response to lipid overload | Plasma | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
75 | Vesiclepedia_2743 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
76 | Vesiclepedia_3253 | 34580290 | Mus musculus | Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles | Kidney medullary cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
77 | Vesiclepedia_1832 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
78 | Vesiclepedia_1520 | 33953168 | Homo sapiens | Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation | Mast cells | miRNA | ExoQuick Kit | Extracellular vesicles | Small EVs |
79 | Vesiclepedia_898 | 26100252 | Homo sapiens | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts | Chronic lymphocytic leukemia cells | miRNA | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
80 | Vesiclepedia_325 | 19289371 | Homo sapiens | Exosomal microRNA: a diagnostic marker for lung cancer | Plasma | miRNA | Size exclusion chromatography Immunobeads (EpCAM) |
Exosomes | EVs |
81 | Vesiclepedia_2457 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation | Apoptotic bodies | Large EVs |
82 | Vesiclepedia_2497 | 34329193 | Homo sapiens | CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis | Breast cancer cells |
Protein miRNA circRNA |
Total Exosome Isolation Reagent | Exosomes | EVs |
83 | Vesiclepedia_334 | 20976003 | Homo sapiens | Selective release of microRNA species from normal and malignant mammary epithelial cells | Breast cancer cells |
Protein miRNA |
Differential centrifugation Filtration |
Exosomes | EVs |
84 | Vesiclepedia_108 | 21601258 | Homo sapiens | Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. | Ascites |
Protein miRNA |
Differential centrifugation Sucrose density gradient Immunobeads (EpCAM, CD24) |
Exosomes | EVs |
85 | Vesiclepedia_2487 | 34388111 | Homo sapiens | miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis | Monocytic leukemia cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
86 | Vesiclepedia_1831 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
87 | Vesiclepedia_2437 | 29335551 | Homo sapiens | Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer | Liver cancer cells |
Protein miRNA |
Filtration Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
88 | Vesiclepedia_2735 | 35545056 | Mus musculus | MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis | Bone marrow cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
89 | Vesiclepedia_321 | 19951903 | Homo sapiens | MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome | Plasma | miRNA | Differential centrifugation Filtration |
Microvesicles | EVs |
90 | Vesiclepedia_3265 | 34654817 | Mus musculus | Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors | Microglia | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Small extracellular vesicles | Small EVs |
91 | Vesiclepedia_2351 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
92 | Vesiclepedia_2746 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
93 | Vesiclepedia_2465 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Serum | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
94 | Vesiclepedia_1797 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Neuroblastoma cells | miRNA | Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
95 | Vesiclepedia_2338 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Plasma | miRNA | ExoQuick Kit Centrifugation |
Exosomes | Small EVs |
96 | Vesiclepedia_3462 | 31451800 | Homo sapiens | Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories | Cardiosphere-derived cells | miRNA | Filtration Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
97 | Vesiclepedia_2354 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Stromal vascular fraction | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
98 | Vesiclepedia_2468 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
99 | Vesiclepedia_1038 | 29887978 | Homo sapiens | Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. | Serum |
Protein miRNA |
miRCURY Exosome Isolation Kit | Extracellular vesicles | EVs |
100 | Vesiclepedia_656 | 28753793 | Homo sapiens | MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma. | Serum | miRNA | Total Exosome Isolation Kit Differential centrifugation Ultracentrifugation Immunobeads (EpCAM) |
Exosomes | EVs |
101 | Vesiclepedia_1204 | 27780738 | Homo sapiens | Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. | Serum | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
102 | Vesiclepedia_3142 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Lung epithelial cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
103 | Vesiclepedia_3244 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
104 | Vesiclepedia_1324 | 33431899 | Mus musculus | High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance | Faeces |
Protein Lipid miRNA |
Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
105 | Vesiclepedia_2602 | 35351860 | Homo sapiens | Bone marrow mesenchymal stem cell-derived exosomal microRNA-381-3p alleviates vascular calcification in chronic kidney disease by targeting NFAT5 | Bone marrow mesenchymal stem cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
106 | Vesiclepedia_329 | 20304794 | Homo sapiens | Functional delivery of viral miRNAs via exosomes | B cells | miRNA | Differential centrifugation | Exosomes | EVs |
107 | Vesiclepedia_2305 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | Monocytes | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
108 | Vesiclepedia_1527 | 33752173 | Homo sapiens | Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
109 | Vesiclepedia_1792 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Neuroblastoma cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
110 | Vesiclepedia_2350 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Stromal vascular fraction | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
111 | Vesiclepedia_3161 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells | miRNA | Differential centrifugation | Microvesicles | Large EVs |
112 | Vesiclepedia_1344 | 33009394 | Homo sapiens | Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p | Platelets |
Protein miRNA |
Ficoll-Hypaque density gradient centrifugation Differential centrifugation Filtration |
Platelet-derived microparticles | EV-like nanoparticles |
113 | Vesiclepedia_1818 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
114 | Vesiclepedia_1827 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells |
Protein miRNA |
Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
115 | Vesiclepedia_514 | 23539611 | Homo sapiens | microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy. | Seminal fluid | miRNA | - | Microvesicles | EVs |
116 | Vesiclepedia_3454 | 31451800 | Homo sapiens | Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories | Cardiosphere-derived cells | miRNA | Filtration Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
117 | Vesiclepedia_3231 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
118 | Vesiclepedia_2029 | 35986010 | Homo sapiens | Exosomal miR-155-5p derived from glioma stem-like cells promotes mesenchymal transition via targeting ACOT12 | Glioblastoma cells |
Protein miRNA |
Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
119 | Vesiclepedia_155 | 21939504 | Homo sapiens | Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells | Macrophage | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Microvesicles | EVs |
120 | Vesiclepedia_2310 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | Natural killer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
121 | Vesiclepedia_2737 | 35545056 | Homo sapiens | MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
122 | Vesiclepedia_1807 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
123 | Vesiclepedia_3153 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells |
Protein miRNA |
Differential centrifugation | Microvesicles | Large EVs |
124 | Vesiclepedia_1254 | 24468161 | Homo sapiens | Molecular characterization of exosome-like vesicles from breast cancer cells. | Breast cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Extracellular vesicles | EVs |
125 | Vesiclepedia_657 | 28753793 | Homo sapiens | MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma. | Serum | miRNA | Total Exosome Isolation Kit Differential centrifugation Ultracentrifugation Immunobeads (EpCAM) |
Exosomes | EVs |
126 | Vesiclepedia_2474 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
127 | Vesiclepedia_1802 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Neuroblastoma cells | miRNA | Size exclusion chromatography | Extracellular vesicles | Small EVs |
128 | Vesiclepedia_2786 | 35304471 | Mus musculus | Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox | Bone | miRNA | Differential centrifugation Filtration Ultracentrifugation Centrifugal ultrafiltration OptiPrep density gradient centrifugation |
Extracellular vesicles | Small EVs |
129 | Vesiclepedia_2460 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Serum | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
130 | Vesiclepedia_1796 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Neuroblastoma cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
131 | Vesiclepedia_3533 | - | Homo sapiens | Small RNA Sequencing of Circulating Small Extracellular Vesicle MicroRNAs in Patients with Amyotrophic Lateral Sclerosis | Serum | miRNA | ExoEasy | Exosomes | Small EVs |
132 | Vesiclepedia_1588 | 33692129 | Macaca fascicularis | Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates | Mesenchymal stem cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Small extracellular vesicles | Small EVs |
133 | Vesiclepedia_1175 | 29854963 | Homo sapiens | Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. | Urine | miRNA | qEV size-exclusion column | Extracellular vesicles | EVs |
134 | Vesiclepedia_2490 | 34388111 | Homo sapiens | miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis | Monocytic leukemia cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
135 | Vesiclepedia_2575 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
136 | Vesiclepedia_1339 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | Liver | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
137 | Vesiclepedia_2748 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
138 | Vesiclepedia_2594 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
139 | Vesiclepedia_343 | 22965126 | Mus musculus | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. | Neuronal cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
140 | Vesiclepedia_1822 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
141 | Vesiclepedia_336 | 20976003 | Homo sapiens | Selective release of microRNA species from normal and malignant mammary epithelial cells | Breast cancer cells |
Protein miRNA |
Differential centrifugation Filtration |
Exosomes | EVs |
142 | Vesiclepedia_3162 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
143 | Vesiclepedia_1196 | 27883272 | Homo sapiens | Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. | Plasma |
miRNA Metabolites |
ExoQuick | Exosomes | EVs |
144 | Vesiclepedia_2595 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
145 | Vesiclepedia_2592 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
146 | Vesiclepedia_3467 | 31451800 | Homo sapiens | Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories | Cardiosphere-derived cells | miRNA | Filtration Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
147 | Vesiclepedia_182 | 20668554 | Homo sapiens | Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs | Liver stem cells | miRNA | Differential centrifugation Ultracentrifugation |
Microvesicles | EVs |
148 | Vesiclepedia_1501 | 33953168 | Homo sapiens | Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation | Serum |
Protein miRNA |
ExoQuick Kit | Extracellular vesicles | Small EVs |
149 | Vesiclepedia_667 | 29956871 | Homo sapiens | Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis | Bronchoalveolar lavage fluid | miRNA | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
150 | Vesiclepedia_2451 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Ultracentrifugation |
Microvesicles | Large EVs |
151 | Vesiclepedia_156 | 21939504 | Homo sapiens | Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells | Macrophage | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Microvesicles | EVs |
152 | Vesiclepedia_2280 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma | miRNA | Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
153 | Vesiclepedia_533 | 23803555 | Bos taurus | Epididymosomes Convey Different Repertoires of MicroRNAs Throughout the Bovine Epididymis. | Cauda luminal fluid | miRNA | - | Membrane vesicles | EVs |
154 | Vesiclepedia_1435 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
155 | Vesiclepedia_1236 | 25421927 | Heligmosomoides polygyrus | Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. | Heligmosomoides polygyrus |
miRNA Protein |
Filtration Ultracentrifugation |
Exosomes | EVs |
156 | Vesiclepedia_435 | 22031862 | Mus musculus | Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. | Dendritic cells | miRNA | - | Exosomes/Nanovesicles | EVs |
157 | Vesiclepedia_322 | 19951903 | Homo sapiens | MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome | Plasma | miRNA | Differential centrifugation Filtration |
Microvesicles | EVs |
158 | Vesiclepedia_2439 | 29335551 | Homo sapiens | Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer | Liver cancer cells |
Protein miRNA |
Filtration Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
159 | Vesiclepedia_2353 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
160 | Vesiclepedia_3245 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
161 | Vesiclepedia_3045 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Plasma |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
162 | Vesiclepedia_1274 | 23807490 | Homo sapiens | Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells. | Glioblastoma cells |
Protein miRNA |
Differential centrifugation | Microvesicles | EVs |
163 | Vesiclepedia_1439 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
164 | Vesiclepedia_2784 | 35304471 | Mus musculus | Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox | Bone | miRNA | ExoQuick Kit | Extracellular vesicles | Small EVs |
165 | Vesiclepedia_1789 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Neuroblastoma cells | miRNA | Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
166 | Vesiclepedia_1235 | 25421927 | Heligmosomoides polygyrus | Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. | Heligmosomoides polygyrus |
miRNA Protein |
Filtration Ultracentrifugation |
Exosomes | EVs |
167 | Vesiclepedia_86 | 20949044 | Homo sapiens | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line | Colorectal cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
168 | Vesiclepedia_1821 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
169 | Vesiclepedia_2491 | 34370714 | Homo sapiens | MiR-195-5p and miR-205-5p in extracellular vesicles isolated from diabetic foot ulcer wound fluid decrease angiogenesis by inhibiting VEGFA expression | Wound fluid |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
170 | Vesiclepedia_1033 | 29887978 | Homo sapiens | Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. | Serum |
Protein miRNA |
qEV size-exclusion column | Extracellular vesicles | EVs |
171 | Vesiclepedia_2276 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma |
Protein miRNA |
Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
172 | Vesiclepedia_1800 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Neuroblastoma cells | miRNA | Size exclusion chromatography | Extracellular vesicles | Small EVs |
173 | Vesiclepedia_45 | 18589210 | Homo sapiens | MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. | Serum |
Protein miRNA |
Ultracentrifugation Immunobeads (EpCAM) |
Exosomes | EVs |
174 | Vesiclepedia_1518 | 33953168 | Homo sapiens | Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation | Serum | miRNA | ExoQuick Kit | Extracellular vesicles | Small EVs |
175 | Vesiclepedia_2306 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | Monocytes | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
176 | Vesiclepedia_3238 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
177 | Vesiclepedia_3262 | 34654817 | Rattus norvegicus | Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors | Plasma | miRNA | ExoQuick Kit | Small extracellular vesicles | EVs |
178 | Vesiclepedia_3339 | 34887515 | Homo sapiens | Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation |
Exomeres | EV-like nanoparticles |
179 | Vesiclepedia_3228 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
180 | Vesiclepedia_1489 | 32024826 | Mus musculus | Liver governs adipose remodelling via extracellular vesicles in response to lipid overload | Plasma | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
181 | Vesiclepedia_117 | 21505438 | Homo sapiens | Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. | Dendritic cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
182 | Vesiclepedia_1824 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Serum | miRNA | Total Exosome Isolation Kit | Exosomes | Small EVs |
183 | Vesiclepedia_2352 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Stromal vascular fraction | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
184 | Vesiclepedia_1036 | 29887978 | Homo sapiens | Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. | Serum |
Protein miRNA |
Exo-spin | Extracellular vesicles | EVs |
185 | Vesiclepedia_2320 | 31762962 | Homo sapiens | Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers | Lung epithelial cells | miRNA | Cell culture media exosome purification and RNA isolation Kit | Exosomes | Small EVs |
186 | Vesiclepedia_1830 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
187 | Vesiclepedia_3239 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
188 | Vesiclepedia_1479 | 32024826 | Mus musculus | Liver governs adipose remodelling via extracellular vesicles in response to lipid overload | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
189 | Vesiclepedia_1790 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Neuroblastoma cells | miRNA | Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
190 | Vesiclepedia_1177 | 29854963 | Homo sapiens | Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. | Urine | miRNA | qEV size-exclusion column | Extracellular vesicles | EVs |
191 | Vesiclepedia_3054 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Plasma | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
192 | Vesiclepedia_1820 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
193 | Vesiclepedia_3340 | 34887515 | Homo sapiens | Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation |
Supermeres | EV-like nanoparticles |
194 | Vesiclepedia_1539 | 33658392 | Homo sapiens | Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma | Lung epithelial cells | miRNA | Minute High-Efficiency Exosome Precipitation Reagent Filtration |
Exosomes | Small EVs |
195 | Vesiclepedia_2793 | 35304471 | Mus musculus | Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation Centrifugal ultrafiltration OptiPrep density gradient centrifugation |
Extracellular vesicles | Small EVs |
196 | Vesiclepedia_2452 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells |
Protein miRNA |
Centrifugation | Apoptotic bodies | Large EVs |
197 | Vesiclepedia_1897 | 36260670 | Mus musculus | Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice | Mesenchymal stem cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
198 | Vesiclepedia_2747 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
199 | Vesiclepedia_2343 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
200 | Vesiclepedia_1337 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | White adipose tissue | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
201 | Vesiclepedia_2593 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung epithelial cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
202 | Vesiclepedia_2450 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation | Apoptotic bodies | Large EVs |
203 | Vesiclepedia_1836 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
204 | Vesiclepedia_1025 | 22327366 | Homo sapiens | Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. | Vascular endothelial cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | EVs |
205 | Vesiclepedia_3414 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | miRNA | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
206 | Vesiclepedia_1825 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Serum | miRNA | Total Exosome Isolation Kit | Exosomes | Small EVs |
207 | Vesiclepedia_666 | 29956871 | Homo sapiens | Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis | Bronchoalveolar lavage fluid | miRNA | Differential centrifugation Ultracentrifugation Filtration |
Microvesicles | EVs |
208 | Vesiclepedia_1811 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
209 | Vesiclepedia_2742 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
210 | Vesiclepedia_1198 | 27883272 | Homo sapiens | Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. | Serum |
miRNA Metabolites |
ExoQuick | Exosomes | EVs |
211 | Vesiclepedia_186 | 22116803 | Equus caballus | Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle | Follicular fluid |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Microvesicles | EVs |
212 | Vesiclepedia_1812 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Serum | miRNA | ExoQuick Kit | Exosomes | Small EVs |
213 | Vesiclepedia_2783 | 35304471 | Mus musculus | Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox | Bone | miRNA | ExoQuick Kit | Extracellular vesicles | Small EVs |
214 | Vesiclepedia_1205 | 27780738 | Homo sapiens | Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. | Serum | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
215 | Vesiclepedia_2753 | 35173168 | Homo sapiens | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
216 | Vesiclepedia_2752 | 35173168 | Homo sapiens | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
217 | Vesiclepedia_3226 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
218 | Vesiclepedia_2473 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
219 | Vesiclepedia_2455 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Ultracentrifugation |
Microvesicles | Large EVs |
220 | Vesiclepedia_1521 | 33953168 | Homo sapiens | Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation | Embryonic kidney cells | miRNA | ExoQuick Kit | Extracellular vesicles | Small EVs |
221 | Vesiclepedia_331 | 19627513 | Homo sapiens | Exosomes from human saliva as a source of microRNA biomarkers | Saliva |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
222 | Vesiclepedia_1349 | 33009394 | Homo sapiens | Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p | Platelets | miRNA | Ficoll-Hypaque density gradient centrifugation Differential centrifugation Filtration |
Platelet-derived microparticles | EV-like nanoparticles |
223 | Vesiclepedia_1031 | 29887978 | Homo sapiens | Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. | Serum |
Protein miRNA |
exoEasy columns | Extracellular vesicles | EVs |
224 | Vesiclepedia_3411 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | miRNA | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
225 | Vesiclepedia_3459 | 31451800 | Homo sapiens | Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories | Primary cardiosphere-derived cells | miRNA | Filtration Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
226 | Vesiclepedia_1182 | 28684402 | Homo sapiens | BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells | Melanoma cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | EVs |
227 | Vesiclepedia_474 | 23056502 | Homo sapiens | Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. | Melanoma cells | miRNA | - | Exosomes | EVs |
228 | Vesiclepedia_2278 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma | miRNA | Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
229 | Vesiclepedia_3255 | 34580290 | Mus musculus | Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles | Kidney medullary cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
230 | Vesiclepedia_2341 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
231 | Vesiclepedia_1794 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Neuroblastoma cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
232 | Vesiclepedia_3047 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Monocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
233 | Vesiclepedia_2744 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
234 | Vesiclepedia_1526 | 33479185 | Homo sapiens | Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke | Mesenchymal stem cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
235 | Vesiclepedia_209 | 21435393 | Rattus norvegicus | Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis | Adipocytes |
mRNA miRNA |
Differential centrifugation Immunobeads (Gce1/CD73) |
Microvesicles | EVs |
236 | Vesiclepedia_3225 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
237 | Vesiclepedia_753 | 29963269 | Homo sapiens | Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury | Hepatoma cells | miRNA | Total Exosome Isolation Kit Differential centrifugation |
Exosomes | EVs |
238 | Vesiclepedia_875 | 24614226 | Ovis aries | Extracellular vesicles in luminal fluid of the ovine uterus | Uterine luminal fluid | miRNA | Differential centrifugation Filtration ExoQuick |
Extracellular vesicles | EVs |
239 | Vesiclepedia_82 | 20949044 | Homo sapiens | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line | Stomach cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
240 | Vesiclepedia_2788 | 35304471 | Homo sapiens | Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation Centrifugal ultrafiltration OptiPrep density gradient centrifugation |
Extracellular vesicles | Small EVs |
241 | Vesiclepedia_116 | 21505438 | Homo sapiens | Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. | B cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
242 | Vesiclepedia_1255 | 24468161 | Homo sapiens | Molecular characterization of exosome-like vesicles from breast cancer cells. | Breast cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Extracellular vesicles | EVs |
243 | Vesiclepedia_1815 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Serum | miRNA | ExoQuick Kit | Exosomes | Small EVs |
244 | Vesiclepedia_15 | 17486113 | Mus musculus Homo sapiens |
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. | Mast cells |
Protein mRNA miRNA |
Filtration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
245 | Vesiclepedia_2739 | 35513391 | Homo sapiens | Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1 | Posterior longitudinal ligament |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Small extracellular vesicles | Small EVs |
246 | Vesiclepedia_3463 | 31451800 | Homo sapiens | Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories | Cardiosphere-derived cells | miRNA | Filtration Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
247 | Vesiclepedia_2213 | 37043568 | Bos taurus | Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis | Bovine milk | miRNA | Differential centrifugation Ultracentrifugation Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
248 | Vesiclepedia_1165 | 29904572 | Bos taurus | A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. | Bovine milk |
Protein miRNA |
Differential centrifugation Density gradient centrifugation |
Extracellular vesicles | EVs |
249 | Vesiclepedia_3165 | 34772807 | Clonorchis sinensis | Csi-let-7a-5p delivered by extracellular vesicles from a liver fluke activates M1-like macrophages and exacerbates biliary injuries | Clonorchis sinensis | miRNA | Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
250 | Vesiclepedia_3232 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
251 | Vesiclepedia_1200 | 27780738 | Homo sapiens | Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. | Cerebrospinal fluid | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
252 | Vesiclepedia_3048 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Glial cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
253 | Vesiclepedia_1538 | 33658392 | Homo sapiens | Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma | Lung cancer cells |
Protein miRNA |
Minute High-Efficiency Exosome Precipitation Reagent Filtration |
Exosomes | Small EVs |
254 | Vesiclepedia_2030 | 35986010 | Homo sapiens | Exosomal miR-155-5p derived from glioma stem-like cells promotes mesenchymal transition via targeting ACOT12 | Glial cells |
Protein miRNA |
Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
255 | Vesiclepedia_1516 | 33953168 | Homo sapiens | Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation | Serum | miRNA | ExoQuick Kit | Extracellular vesicles | Small EVs |
256 | Vesiclepedia_3227 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
257 | Vesiclepedia_1517 | 33953168 | Homo sapiens | Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation | Serum | miRNA | ExoQuick Kit | Extracellular vesicles | Small EVs |
258 | Vesiclepedia_2368 | 36759608 | Mus musculus | Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo | Adipocytes |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
259 | Vesiclepedia_3160 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
260 | Vesiclepedia_112 | 21601258 | Homo sapiens | Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. | Serum |
Protein miRNA |
Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
261 | Vesiclepedia_1459 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
262 | Vesiclepedia_756 | 28357077 | Mus musculus | Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells | Plasma | miRNA | Total Exosome Isolation Kit Differential centrifugation |
Exosomes | EVs |
263 | Vesiclepedia_3246 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung epithelial cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
264 | Vesiclepedia_532 | 23803555 | Bos taurus | Epididymosomes Convey Different Repertoires of MicroRNAs Throughout the Bovine Epididymis. | Epithelial cells | miRNA | - | Membrane vesicles | EVs |
265 | Vesiclepedia_1809 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
266 | Vesiclepedia_3375 | 34931471 | Mus musculus | Extracellular vesicles derived from tumour cells as a trigger of energy crisis in the skeletal muscle | Colon cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Microvesicles | Small EVs |
267 | Vesiclepedia_1461 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
268 | Vesiclepedia_2492 | 34370714 | Homo sapiens | MiR-195-5p and miR-205-5p in extracellular vesicles isolated from diabetic foot ulcer wound fluid decrease angiogenesis by inhibiting VEGFA expression | Wound fluid |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
269 | Vesiclepedia_2475 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
270 | Vesiclepedia_346 | 22965126 | Mus musculus | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. | Neuronal cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
271 | Vesiclepedia_2332 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
272 | Vesiclepedia_3374 | 34931471 | Mus musculus | Extracellular vesicles derived from tumour cells as a trigger of energy crisis in the skeletal muscle | Plasma | miRNA | Differential centrifugation Ultracentrifugation |
Microvesicles | Small EVs |
273 | Vesiclepedia_1476 | 32024826 | Mus musculus | Liver governs adipose remodelling via extracellular vesicles in response to lipid overload | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
274 | Vesiclepedia_1346 | 33009394 | Homo sapiens | Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p | Platelets | miRNA | Ficoll-Hypaque density gradient centrifugation Differential centrifugation Filtration |
Platelet-derived microparticles | EV-like nanoparticles |
275 | Vesiclepedia_1183 | 28684402 | Homo sapiens | BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells | Melanoma cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | EVs |
276 | Vesiclepedia_3412 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | miRNA | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
277 | Vesiclepedia_2750 | 35173168 | Homo sapiens | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
278 | Vesiclepedia_1203 | 27780738 | Homo sapiens | Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. | Serum | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
279 | Vesiclepedia_2308 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | Monocytes | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
280 | Vesiclepedia_1170 | 29907695 | Mus musculus | Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. | Melanoma cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | EVs |
281 | Vesiclepedia_515 | 23539611 | Homo sapiens | microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy. | Seminal fluid | miRNA | - | Microvesicles | EVs |
282 | Vesiclepedia_2489 | 34388111 | Homo sapiens | miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis | Monocytic leukemia cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
283 | Vesiclepedia_2304 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | Monocytes | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
284 | Vesiclepedia_2446 | 34489604 | Mus musculus | Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 | Hepatocytes |
Protein miRNA |
Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
285 | Vesiclepedia_2442 | 34489604 | Mus musculus | Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 | Hepatocytes |
Protein miRNA |
Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
286 | Vesiclepedia_1515 | 33953168 | Homo sapiens | Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation | Serum | miRNA | ExoQuick Kit | Extracellular vesicles | Small EVs |
287 | Vesiclepedia_2872 | 30918259 | Homo sapiens | Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A | Breast cancer cells | miRNA | Differential centrifugation Filtration ExoQuick Kit |
Small extracellular vesicles | Small EVs |
288 | Vesiclepedia_345 | 22965126 | Mus musculus | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. | Neuronal cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
289 | Vesiclepedia_1477 | 32024826 | Mus musculus | Liver governs adipose remodelling via extracellular vesicles in response to lipid overload | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
290 | Vesiclepedia_1463 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
291 | Vesiclepedia_2339 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
292 | Vesiclepedia_1469 | 32132543 | Homo sapiens | Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension | Pulmonary artery endothelial cells | miRNA | miRCURY Exosome Isolation Kit Centrifugation Sonication |
Exosomes | Small EVs |
293 | Vesiclepedia_1787 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Primary cortical neurons |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
294 | Vesiclepedia_2337 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Plasma | miRNA | ExoQuick Kit Centrifugation |
Exosomes | Small EVs |
295 | Vesiclepedia_2277 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma | miRNA | Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
296 | Vesiclepedia_3243 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
297 | Vesiclepedia_3249 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
298 | Vesiclepedia_1492 | 32024826 | Homo sapiens | Liver governs adipose remodelling via extracellular vesicles in response to lipid overload | Plasma | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
299 | Vesiclepedia_1530 | 33752173 | Homo sapiens | Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression | Breast cancer cells | miRNA | Total Exosome Isolation Kit Centrifugation |
Exosomes | Small EVs |
300 | Vesiclepedia_2613 | 35443745 | Homo sapiens | Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts | Colorectal cancer cells |
Protein miRNA |
Ultracentrifugation ExoQuick Kit |
Exosomes | Small EVs |
301 | Vesiclepedia_2311 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | B cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
302 | Vesiclepedia_2309 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | Natural killer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
303 | Vesiclepedia_462 | 22849433 | Homo sapiens | Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types. | Embryonic kidney cells | miRNA | - | Extracellular vesicles | EVs |
304 | Vesiclepedia_3458 | 31451800 | Homo sapiens | Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories | Primary cardiosphere-derived cells | miRNA | Filtration Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
305 | Vesiclepedia_2463 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Serum | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
306 | Vesiclepedia_547 | 24009880 | Homo sapiens | Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. | Mast cells | miRNA | - | Exosomes/Extracellular vesicles | EVs |
307 | Vesiclepedia_2445 | 34489604 | Mus musculus | Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 | Hepatocytes |
Protein miRNA |
Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
308 | Vesiclepedia_2303 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | Monocytes | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
309 | Vesiclepedia_1490 | 32024826 | Homo sapiens | Liver governs adipose remodelling via extracellular vesicles in response to lipid overload | Plasma | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
310 | Vesiclepedia_2815 | 34168137 | Bos taurus | Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis | Bovine milk |
Protein mRNA miRNA tRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
311 | Vesiclepedia_1336 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | Plasma |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
312 | Vesiclepedia_3145 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Plasma | miRNA | ExoQuick Kit | Exosomes | EVs |
313 | Vesiclepedia_2787 | 35304471 | Mus musculus | Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox | Bone | miRNA | Differential centrifugation Filtration Ultracentrifugation Centrifugal ultrafiltration OptiPrep density gradient centrifugation |
Extracellular vesicles | Small EVs |
314 | Vesiclepedia_3163 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells | miRNA | Differential centrifugation | Microvesicles | Large EVs |
315 | Vesiclepedia_338 | 20621060 | Rattus norvegicus | Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation | Adipocytes |
mRNA miRNA |
Differential centrifugation Ultracentrifugation |
Microvesicles | EVs |
316 | Vesiclepedia_1468 | 32132543 | Homo sapiens | Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension | Pulmonary artery endothelial cells | miRNA | miRCURY Exosome Isolation Kit Centrifugation Sonication |
Exosomes | Small EVs |
317 | Vesiclepedia_455 | 22682234 | Homo sapiens | Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits. | Leukemia cells | miRNA | - | Membrane vesicles/Microparticles | EVs |
318 | Vesiclepedia_3338 | 34887515 | Homo sapiens | Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation OptiPrep density gradient centrifugation |
Small extracellular vesicles | Small EVs |
319 | Vesiclepedia_3144 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Plasma | miRNA | ExoQuick Kit | Exosomes | EVs |
320 | Vesiclepedia_3143 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Plasma | miRNA | ExoQuick Kit | Exosomes | EVs |
321 | Vesiclepedia_3261 | 34654817 | Rattus norvegicus | Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors | Plasma |
Protein miRNA |
ExoQuick Kit | Small extracellular vesicles | EVs |
322 | Vesiclepedia_1447 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
323 | Vesiclepedia_2871 | 30918259 | Homo sapiens | Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A | Breast cancer cells | miRNA | Differential centrifugation Filtration ExoQuick Kit |
Small extracellular vesicles | Small EVs |
324 | Vesiclepedia_1438 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
325 | Vesiclepedia_1788 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Primary cortical neurons | miRNA | Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
326 | Vesiclepedia_2214 | 37043568 | Homo sapiens | Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis | Breast milk | miRNA | Differential centrifugation Ultracentrifugation Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
327 | Vesiclepedia_319 | 20615901 | Homo sapiens | Export of microRNAs and microRNA-protective protein by mammalian cells | Lung cancer cells | miRNA | Differential centrifugation | Microvesicles | EVs |
328 | Vesiclepedia_2283 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma | miRNA | Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
329 | Vesiclepedia_1167 | 29907695 | Mus musculus | Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. | Melanoma cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | EVs |
330 | Vesiclepedia_109 | 21601258 | Homo sapiens | Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. | Malignant pleural effusions |
Protein miRNA |
Differential centrifugation Sucrose density gradient Immunobeads (EpCAM) |
Exosomes | EVs |
331 | Vesiclepedia_3229 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
332 | Vesiclepedia_2598 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
333 | Vesiclepedia_2459 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
334 | Vesiclepedia_2300 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | Monocytes |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
335 | Vesiclepedia_1348 | 33009394 | Homo sapiens | Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p | Platelets | miRNA | Ficoll-Hypaque density gradient centrifugation Differential centrifugation Filtration |
Platelet-derived microparticles | EV-like nanoparticles |
336 | Vesiclepedia_1462 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
337 | Vesiclepedia_2472 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
338 | Vesiclepedia_3460 | 31451800 | Homo sapiens | Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories | Dermal fibroblast cells | miRNA | Filtration Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
339 | Vesiclepedia_1178 | 29854963 | Homo sapiens | Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. | Urine | miRNA | qEV size-exclusion column | Extracellular vesicles | EVs |
340 | Vesiclepedia_658 | 28753793 | Homo sapiens | MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma. | Serum | miRNA | Total Exosome Isolation Kit Differential centrifugation Ultracentrifugation Immunobeads (EpCAM) |
Exosomes | EVs |
341 | Vesiclepedia_1184 | 28684402 | Homo sapiens | BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells | Melanoma cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | EVs |
342 | Vesiclepedia_175 | 19002258 | Homo sapiens | Detection of microRNA Expression in Human Peripheral Blood Microvesicles | Plasma | miRNA | Differential centrifugation | Microvesicles | EVs |
343 | Vesiclepedia_190 | 22116803 | Equus caballus | Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle | Follicular fluid | miRNA | Differential centrifugation ExoQuick |
Exosomes | EVs |
344 | Vesiclepedia_1513 | 33953168 | Homo sapiens | Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation | Serum | miRNA | ExoQuick Kit | Extracellular vesicles | Small EVs |
345 | Vesiclepedia_1441 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
346 | Vesiclepedia_1442 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
347 | Vesiclepedia_3376 | 34931471 | Mus musculus | Extracellular vesicles derived from tumour cells as a trigger of energy crisis in the skeletal muscle | Plasma | miRNA | Differential centrifugation Ultracentrifugation |
Microvesicles | Small EVs |
348 | Vesiclepedia_332 | 19627513 | Homo sapiens | Exosomes from human saliva as a source of microRNA biomarkers | Saliva | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
349 | Vesiclepedia_1816 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Serum | miRNA | ExoQuick Kit | Exosomes | Small EVs |
350 | Vesiclepedia_2601 | 35351860 | Homo sapiens | Bone marrow mesenchymal stem cell-derived exosomal microRNA-381-3p alleviates vascular calcification in chronic kidney disease by targeting NFAT5 | Bone marrow mesenchymal stem cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
351 | Vesiclepedia_531 | 23803555 | Bos taurus | Epididymosomes Convey Different Repertoires of MicroRNAs Throughout the Bovine Epididymis. | Caput luminal fluid | miRNA | - | Membrane vesicles | EVs |
352 | Vesiclepedia_1323 | 33431899 | Mus musculus | High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance | Faeces |
Protein Lipid miRNA |
Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
353 | Vesiclepedia_3410 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | miRNA | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
354 | Vesiclepedia_1173 | 29881354 | Rattus norvegicus | Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content. | Serum |
Protein miRNA |
ExoQuick | Extracellular vesicles | EVs |
355 | Vesiclepedia_2027 | 36455873 | Homo sapiens | Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF | Plasma |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
356 | Vesiclepedia_3455 | 31451800 | Homo sapiens | Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories | Cardiosphere-derived cells | miRNA | Filtration Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
357 | Vesiclepedia_1798 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Neuroblastoma cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
358 | Vesiclepedia_2500 | 34329193 | Homo sapiens | CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis | Breast cancer cells | miRNA | Total Exosome Isolation Reagent | Exosomes | EVs |
359 | Vesiclepedia_357 | 24352158 | Homo sapiens | Characterization and deep sequencing analysis of exosomal miRNA in human urine | Urine | miRNA | Differential centrifugation Norgen Biotek Exosome kit |
Exosomes | EVs |
360 | Vesiclepedia_3140 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Plasma |
Protein miRNA |
ExoQuick Kit | Exosomes | EVs |
361 | Vesiclepedia_206 | 21435393 | Rattus norvegicus | Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis | Adipocytes |
mRNA miRNA |
Differential centrifugation Immunobeads (Gce1/CD73) |
Microvesicles | EVs |
362 | Vesiclepedia_1896 | 36260670 | Mus musculus | Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice | Mesenchymal stem cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
363 | Vesiclepedia_3230 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
364 | Vesiclepedia_1502 | 33953168 | Homo sapiens | Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation | Serum |
Protein miRNA |
ExoQuick Kit | Extracellular vesicles | Small EVs |
365 | Vesiclepedia_3413 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | miRNA | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
366 | Vesiclepedia_342 | 22965126 | Mus musculus | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. | Neuronal cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
367 | Vesiclepedia_1808 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | ExoQuick Kit | Exosomes | Small EVs |
368 | Vesiclepedia_1528 | 33752173 | Homo sapiens | Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
369 | Vesiclepedia_2499 | 34329193 | Homo sapiens | CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis | Breast cancer cells | miRNA | Total Exosome Isolation Reagent | Exosomes | EVs |
370 | Vesiclepedia_340 | 20615901 | Homo sapiens | Export of microRNAs and microRNA-protective protein by mammalian cells | Lung cancer cells | miRNA | Differential centrifugation | Exosomes | EVs |
371 | Vesiclepedia_3380 | 31848325 | Rattus norvegicus | Insulin-like growth factor-1 enchances neuroprotective effects of neural stem cell exosomes after spinal cord injury via an miR-219a-2-3p/YY1 mechanism | Neural stem cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
372 | Vesiclepedia_1481 | 32024826 | Mus musculus | Liver governs adipose remodelling via extracellular vesicles in response to lipid overload | Hepatocytes |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
373 | Vesiclepedia_2591 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
374 | Vesiclepedia_3141 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
375 | Vesiclepedia_2597 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung epithelial cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
376 | Vesiclepedia_3154 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
377 | Vesiclepedia_1444 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
378 | Vesiclepedia_3158 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
379 | Vesiclepedia_2493 | 34370714 | Homo sapiens | MiR-195-5p and miR-205-5p in extracellular vesicles isolated from diabetic foot ulcer wound fluid decrease angiogenesis by inhibiting VEGFA expression | Serum | miRNA | Polyethylene glycol-based precipitation Centrifugation |
Extracellular vesicles | EVs |
380 | Vesiclepedia_1823 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Serum | miRNA | Total Exosome Isolation Kit | Exosomes | Small EVs |
381 | Vesiclepedia_2498 | 34329193 | Homo sapiens | CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis | Breast cancer cells |
Protein miRNA circRNA |
Total Exosome Isolation Reagent | Exosomes | EVs |
382 | Vesiclepedia_2785 | 35304471 | Mus musculus | Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox | Bone | miRNA | Differential centrifugation Filtration Ultracentrifugation Centrifugal ultrafiltration OptiPrep density gradient centrifugation |
Extracellular vesicles | Small EVs |
383 | Vesiclepedia_476 | 23056502 | Homo sapiens | Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. | Melanoma cells | miRNA | - | Exosomes | EVs |
384 | Vesiclepedia_3247 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung epithelial cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
385 | Vesiclepedia_2596 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung epithelial cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
386 | Vesiclepedia_2526 | 34315885 | Mus musculus | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease | Embryonic kidney cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
387 | Vesiclepedia_2612 | 35443745 | Homo sapiens | Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts | Colorectal cancer cells |
Protein miRNA |
Ultracentrifugation ExoQuick Kit |
Exosomes | Small EVs |
388 | Vesiclepedia_330 | 20304794 | Homo sapiens | Functional delivery of viral miRNAs via exosomes | B cells | miRNA | Differential centrifugation | Exosomes | EVs |
389 | Vesiclepedia_2789 | 35304471 | Homo sapiens | Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation Centrifugal ultrafiltration OptiPrep density gradient centrifugation |
Extracellular vesicles | Small EVs |
390 | Vesiclepedia_2449 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells |
Protein miRNA |
Centrifugation Ultracentrifugation |
Extracellular vesicles | EVs |
391 | Vesiclepedia_2462 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Serum | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
392 | Vesiclepedia_3379 | 31848325 | Rattus norvegicus | Insulin-like growth factor-1 enchances neuroprotective effects of neural stem cell exosomes after spinal cord injury via an miR-219a-2-3p/YY1 mechanism | Neural stem cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
393 | Vesiclepedia_2527 | 34315885 | Mus musculus | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease | Kidney epithelial cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
394 | Vesiclepedia_333 | 20976003 | Homo sapiens | Selective release of microRNA species from normal and malignant mammary epithelial cells | Breast cancer cells |
Protein miRNA |
Differential centrifugation Filtration |
Exosomes | EVs |
395 | Vesiclepedia_1077 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | miRNA | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
396 | Vesiclepedia_2346 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
397 | Vesiclepedia_3202 | 34596354 | Homo sapiens | Extracellular vesicles from adipose tissue-derived stem cells alleviate osteoporosis through osteoprotegerin and miR-21-5p | Mesenchymal stem cells |
Protein miRNA |
Tangential flow filtration | Extracellular vesicles | Small EVs |
398 | Vesiclepedia_1201 | 27780738 | Homo sapiens | Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. | Cerebrospinal fluid | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
399 | Vesiclepedia_2745 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
400 | Vesiclepedia_3224 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
401 | Vesiclepedia_2321 | 31762962 | Homo sapiens | Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers | Lung epithelial cells | miRNA | Cell culture media exosome purification and RNA isolation Kit | Exosomes | Small EVs |
402 | Vesiclepedia_874 | 24614226 | Ovis aries | Extracellular vesicles in luminal fluid of the ovine uterus | Uterine luminal fluid | miRNA | Differential centrifugation Filtration ExoQuick |
Extracellular vesicles | EVs |
403 | Vesiclepedia_1035 | 29887978 | Homo sapiens | Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. | Serum |
Protein miRNA |
Exo-spin | Extracellular vesicles | EVs |
404 | Vesiclepedia_1457 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Breast cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
405 | Vesiclepedia_2738 | 35545056 | Homo sapiens | MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
406 | Vesiclepedia_3254 | 34580290 | Mus musculus | Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles | Kidney medullary cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
407 | Vesiclepedia_337 | 20976003 | Homo sapiens | Selective release of microRNA species from normal and malignant mammary epithelial cells | Breast cancer cells | miRNA | Differential centrifugation Filtration |
Exosomes | EVs |
408 | Vesiclepedia_2366 | 36759608 | Mus musculus | Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo | Adipocytes |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
409 | Vesiclepedia_1181 | 28684402 | Homo sapiens | BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells | Melanoma cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | EVs |
410 | Vesiclepedia_1532 | 33752173 | Homo sapiens | Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression | Plasma | miRNA | Total Exosome Isolation Kit Centrifugation |
Exosomes | Small EVs |
411 | Vesiclepedia_755 | 29963269 | Homo sapiens | Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury | Hepatoma cells | miRNA | Total Exosome Isolation Kit Differential centrifugation |
Exosomes | EVs |
412 | Vesiclepedia_3164 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
413 | Vesiclepedia_3049 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Monocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
414 | Vesiclepedia_436 | 22031862 | Mus musculus | Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. | Dendritic cells | miRNA | - | Exosomes/Nanovesicles | EVs |
415 | Vesiclepedia_1589 | 33692129 | Macaca fascicularis | Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates | Mesenchymal stem cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Small extracellular vesicles | Small EVs |
416 | Vesiclepedia_757 | 28357077 | Mus musculus | Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells | Plasma | miRNA | Total Exosome Isolation Kit Differential centrifugation |
Exosomes | EVs |
417 | Vesiclepedia_1341 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | Muscle | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
418 | Vesiclepedia_2522 | 34315885 | Mus musculus | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease | Kidney epithelial cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
419 | Vesiclepedia_204 | 19011622 | Homo sapiens | Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers | Serum |
mRNA miRNA |
Differential centrifugation Ultracentrifugation Filtration |
Microvesicles | EVs |
420 | Vesiclepedia_3406 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph |
Protein miRNA |
Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
421 | Vesiclepedia_1810 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | ExoQuick Kit | Exosomes | Small EVs |
422 | Vesiclepedia_2454 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation | Apoptotic bodies | Large EVs |
423 | Vesiclepedia_1829 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
424 | Vesiclepedia_2581 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
425 | Vesiclepedia_1813 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Serum | miRNA | ExoQuick Kit | Exosomes | Small EVs |
426 | Vesiclepedia_2792 | 35304471 | Mus musculus | Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation Centrifugal ultrafiltration OptiPrep density gradient centrifugation |
Extracellular vesicles | Small EVs |
427 | Vesiclepedia_1335 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | Plasma |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
428 | Vesiclepedia_456 | 22682234 | Homo sapiens | Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits. | Breast cancer cells | miRNA | - | Membrane vesicles/Microparticles | EVs |
429 | Vesiclepedia_3405 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Embryonic cells |
Protein miRNA |
Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
430 | Vesiclepedia_3456 | 31451800 | Homo sapiens | Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories | Fibroblasts | miRNA | Filtration Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
431 | Vesiclepedia_690 | 28170197 | Homo sapiens | Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 | Bone marrow mesenchymal stem cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
432 | Vesiclepedia_115 | 21505438 | Homo sapiens | Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. | T cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
433 | Vesiclepedia_1540 | 33658392 | Homo sapiens | Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma | Lung cancer cells |
Protein miRNA |
Minute High-Efficiency Exosome Precipitation Reagent Filtration |
Exosomes | Small EVs |
434 | Vesiclepedia_344 | 22965126 | Mus musculus | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. | Neuronal cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
435 | Vesiclepedia_1443 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
436 | Vesiclepedia_1338 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | White adipose tissue | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
437 | Vesiclepedia_2313 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | T cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
438 | Vesiclepedia_1460 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
439 | Vesiclepedia_88 | 20949044 | Homo sapiens | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line | Stomach cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
440 | Vesiclepedia_2574 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
441 | Vesiclepedia_1176 | 29854963 | Homo sapiens | Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. | Urine | miRNA | qEV size-exclusion column | Extracellular vesicles | EVs |
442 | Vesiclepedia_3155 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells |
Protein miRNA |
Differential centrifugation | Microvesicles | Large EVs |
443 | Vesiclepedia_3466 | 31451800 | Homo sapiens | Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories | Cardiosphere-derived cells | miRNA | Filtration Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
444 | Vesiclepedia_3457 | 31451800 | Homo sapiens | Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories | Fibroblasts | miRNA | Filtration Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
445 | Vesiclepedia_1835 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
446 | Vesiclepedia_1793 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Neuroblastoma cells | miRNA | Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
447 | Vesiclepedia_2486 | 34388111 | Homo sapiens | miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis | Monocytic leukemia cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
448 | Vesiclepedia_2333 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
449 | Vesiclepedia_1482 | 32024826 | Mus musculus | Liver governs adipose remodelling via extracellular vesicles in response to lipid overload | Hepatocytes |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
450 | Vesiclepedia_1456 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Breast cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
451 | Vesiclepedia_317 | 19266099 | Homo sapiens | Transfer of microRNAs by embryonic stem cell microvesicles | Embryonic stem cells |
mRNA miRNA snRNA |
Differential centrifugation | Microvesicles | EVs |
452 | Vesiclepedia_1480 | 32024826 | Mus musculus | Liver governs adipose remodelling via extracellular vesicles in response to lipid overload | Hepatocytes |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
453 | Vesiclepedia_2440 | 29335551 | Homo sapiens | Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer | Liver cancer cells |
Protein miRNA |
Filtration Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
454 | Vesiclepedia_2438 | 29335551 | Homo sapiens | Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer | Liver cancer cells |
Protein miRNA |
Filtration Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
455 | Vesiclepedia_3159 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells | miRNA | Differential centrifugation | Microvesicles | Large EVs |
456 | Vesiclepedia_1185 | 28042326 | Homo sapiens | Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model. | Synovial mesenchymal stem cells | miRNA | Differential centrifugation Filtration Sucrose density gradient |
Exosomes | EVs |
457 | Vesiclepedia_2580 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
458 | Vesiclepedia_3465 | 31451800 | Homo sapiens | Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories | Cardiosphere-derived cells | miRNA | Filtration Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
459 | Vesiclepedia_2456 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
460 | Vesiclepedia_111 | 21601258 | Homo sapiens | Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. | Serum |
Protein miRNA |
Differential centrifugation Sucrose density gradient Immunobeads (CD24) |
Exosomes | EVs |
461 | Vesiclepedia_3409 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | miRNA | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
462 | Vesiclepedia_203 | 19011622 | Homo sapiens | Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers | Glioblastoma cells |
Protein miRNA mRNA |
Differential centrifugation Ultracentrifugation Filtration |
Microvesicles | EVs |
463 | Vesiclepedia_2322 | 31762962 | Homo sapiens | Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers | Monocytes | miRNA | Cell culture media exosome purification and RNA isolation Kit | Exosomes | Small EVs |
464 | Vesiclepedia_185 | 22116803 | Equus caballus | Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle | Follicular fluid |
Protein miRNA |
Differential centrifugation ExoQuick |
Exosomes | EVs |
465 | Vesiclepedia_758 | 28357077 | Mus musculus | Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells | Osteocytes | miRNA | Total Exosome Isolation Kit Differential centrifugation |
Exosomes | EVs |
466 | Vesiclepedia_181 | 20668554 | Homo sapiens | Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs | Mesenchymal stem cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Microvesicles | EVs |
467 | Vesiclepedia_1529 | 33752173 | Homo sapiens | Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression | Breast cancer cells | miRNA | Total Exosome Isolation Kit Centrifugation |
Exosomes | Small EVs |
468 | Vesiclepedia_1826 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Serum | miRNA | Total Exosome Isolation Kit | Exosomes | Small EVs |
469 | Vesiclepedia_1805 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Serum |
Protein miRNA |
ExoQuick Kit | Exosomes | Small EVs |
470 | Vesiclepedia_2469 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
471 | Vesiclepedia_85 | 20949044 | Homo sapiens | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line | Lung cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
472 | Vesiclepedia_688 | 28170197 | Homo sapiens | Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 | Endometrium-derived mesenchymal stem cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
473 | Vesiclepedia_2444 | 34489604 | Mus musculus | Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 | Hepatocytes |
Protein miRNA |
Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
474 | Vesiclepedia_2028 | 36455873 | Homo sapiens | Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF | Plasma |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
475 | Vesiclepedia_1483 | 32024826 | Mus musculus | Liver governs adipose remodelling via extracellular vesicles in response to lipid overload | Hepatocytes |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
476 | Vesiclepedia_1819 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
477 | Vesiclepedia_2600 | 35136055 | Mus musculus | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
478 | Vesiclepedia_208 | 21435393 | Rattus norvegicus | Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis | Serum |
mRNA miRNA |
Differential centrifugation Sucrose density gradient Immunobeads (Gce1/CD73) |
Microvesicles | EVs |
479 | Vesiclepedia_2501 | 34329193 | Homo sapiens | CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis | Breast cancer cells | miRNA | Total Exosome Isolation Reagent | Exosomes | EVs |
480 | Vesiclepedia_1179 | 29854963 | Homo sapiens | Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. | Urine | miRNA | qEV size-exclusion column | Extracellular vesicles | EVs |
481 | Vesiclepedia_2345 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
482 | Vesiclepedia_1168 | 29907695 | Mus musculus | Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. | Melanoma cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | EVs |
483 | Vesiclepedia_341 | 20615901 | Homo sapiens | Export of microRNAs and microRNA-protective protein by mammalian cells | Epithelial cells | miRNA | Differential centrifugation | Exosomes | EVs |
484 | Vesiclepedia_2733 | 35545056 | Mus musculus | MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis | Bone marrow cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
485 | Vesiclepedia_87 | 20949044 | Homo sapiens | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line | Colorectal cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
486 | Vesiclepedia_1834 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
487 | Vesiclepedia_2342 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
488 | Vesiclepedia_810 | 29932869 | Mus musculus | Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy | Schwann cells | miRNA | Filtration Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
489 | Vesiclepedia_2315 | 31489147 | Homo sapiens | Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles | T cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
490 | Vesiclepedia_2470 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
491 | Vesiclepedia_2578 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
492 | Vesiclepedia_3233 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
493 | Vesiclepedia_3408 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | miRNA | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
494 | Vesiclepedia_2349 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
495 | Vesiclepedia_2323 | 31762962 | Homo sapiens | Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers | Monocytes | miRNA | Cell culture media exosome purification and RNA isolation Kit | Exosomes | Small EVs |
496 | Vesiclepedia_2734 | 35545056 | Mus musculus | MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis | Bone marrow cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Extracellular vesicles | Small EVs |
497 | Vesiclepedia_3237 | 34596365 | Homo sapiens | CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
498 | Vesiclepedia_320 | 20615901 | Homo sapiens | Export of microRNAs and microRNA-protective protein by mammalian cells | Epithelial cells | miRNA | Differential centrifugation | Microvesicles | EVs |
499 | Vesiclepedia_1199 | 27883272 | Homo sapiens | Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. | Serum |
miRNA Metabolites |
ExoQuick | Exosomes | EVs |
500 | Vesiclepedia_2348 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
501 | Vesiclepedia_3260 | 34654817 | Rattus norvegicus | Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors | Plasma |
Protein miRNA |
ExoQuick Kit | Small extracellular vesicles | EVs |
502 | Vesiclepedia_205 | 19011622 | Homo sapiens | Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers | Serum |
mRNA miRNA |
Differential centrifugation Ultracentrifugation Filtration |
Microvesicles | EVs |
503 | Vesiclepedia_2334 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
504 | Vesiclepedia_3241 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
505 | Vesiclepedia_1440 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
506 | Vesiclepedia_668 | 29956871 | Homo sapiens | Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis | Bronchoalveolar lavage fluid | miRNA | Differential centrifugation Ultracentrifugation Filtration |
Microvesicles | EVs |
507 | Vesiclepedia_2582 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
508 | Vesiclepedia_1828 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells |
Protein miRNA |
Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
509 | Vesiclepedia_1458 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Mammary epithelial cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
510 | Vesiclepedia_1234 | 25421927 | Mus musculus | Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. | Serum |
miRNA Protein |
Filtration Ultracentrifugation |
Exosomes | EVs |
511 | Vesiclepedia_1340 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | Liver | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
512 | Vesiclepedia_3464 | 31451800 | Homo sapiens | Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories | Cardiosphere-derived cells | miRNA | Filtration Centrifugal ultrafiltration |
Extracellular vesicles | Small EVs |
513 | Vesiclepedia_1197 | 27883272 | Homo sapiens | Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. | Plasma |
miRNA Metabolites |
ExoQuick | Exosomes | EVs |
514 | Vesiclepedia_3139 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Plasma |
Protein miRNA |
ExoQuick Kit | Exosomes | EVs |
515 | Vesiclepedia_1202 | 27780738 | Homo sapiens | Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. | Cerebrospinal fluid | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
516 | Vesiclepedia_904 | 25053844 | Homo sapiens | Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons | Neuroblastoma cells | miRNA | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
517 | Vesiclepedia_1801 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Neuroblastoma cells | miRNA | Size exclusion chromatography | Extracellular vesicles | Small EVs |
518 | Vesiclepedia_1446 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
519 | Vesiclepedia_3157 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells | miRNA | Differential centrifugation | Microvesicles | Large EVs |
520 | Vesiclepedia_2599 | 35136055 | Homo sapiens | Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
521 | Vesiclepedia_2340 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
522 | Vesiclepedia_2466 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Serum | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
523 | Vesiclepedia_2521 | 34315885 | Mus musculus | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease | Kidney epithelial cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Extracellular vesicles | Small EVs |
524 | Vesiclepedia_2467 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
525 | Vesiclepedia_3264 | 34654817 | Mus musculus | Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors | Microglia | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Small extracellular vesicles | Small EVs |
526 | Vesiclepedia_1350 | 33009394 | Homo sapiens | Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p | Platelets | miRNA | Ficoll-Hypaque density gradient centrifugation Differential centrifugation Filtration |
Platelet-derived microparticles | EV-like nanoparticles |
527 | Vesiclepedia_1541 | 33658392 | Homo sapiens | Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma | Lung cancer cells |
Protein miRNA |
Minute High-Efficiency Exosome Precipitation Reagent Filtration |
Exosomes | Small EVs |
528 | Vesiclepedia_1037 | 29887978 | Homo sapiens | Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. | Serum |
Protein miRNA |
miRCURY Exosome Isolation Kit | Extracellular vesicles | EVs |
529 | Vesiclepedia_1799 | 36594832 | Mus musculus | Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia | Neuroblastoma cells | miRNA | Size exclusion chromatography | Extracellular vesicles | Small EVs |
530 | Vesiclepedia_961 | 26047123 | Bos taurus | Oral administration of bovine milk derived extracellular vesicles attenuates arthritis in two mouse models. | Bovine milk | miRNA | Differential centrifugation Ultracentrifugation Filtration |
Extracellular vesicles | EVs |
531 | Vesiclepedia_1817 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
532 | Vesiclepedia_1445 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
533 | Vesiclepedia_2281 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma | miRNA | Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
534 | Vesiclepedia_3234 | 34596365 | Homo sapiens | Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Small extracellular vesicles | Small EVs |
535 | Vesiclepedia_1448 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Plasma | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
536 | Vesiclepedia_2488 | 34388111 | Homo sapiens | miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis | Monocytic leukemia cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
537 | Vesiclepedia_1531 | 33752173 | Homo sapiens | Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression | Plasma | miRNA | Total Exosome Isolation Kit Centrifugation |
Exosomes | Small EVs |
538 | Vesiclepedia_2282 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma | miRNA | Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
539 | Vesiclepedia_2464 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Serum | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
540 | Vesiclepedia_110 | 21601258 | Homo sapiens | Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. | Ascites |
Protein miRNA |
Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
541 | Vesiclepedia_2448 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Ultracentrifugation |
Extracellular vesicles | EVs |
542 | Vesiclepedia_2791 | 35304471 | Mus musculus | Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox | Liver | miRNA | Differential centrifugation Filtration Ultracentrifugation Centrifugal ultrafiltration OptiPrep density gradient centrifugation |
Extracellular vesicles | Small EVs |
543 | Vesiclepedia_665 | 29956871 | Homo sapiens | Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis | Bronchoalveolar lavage fluid | miRNA | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
544 | Vesiclepedia_1172 | 29881354 | Rattus norvegicus | Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content. | Serum |
Protein miRNA |
ExoQuick | Extracellular vesicles | EVs |
545 | Vesiclepedia_2749 | 35173168 | Homo sapiens | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
546 | Vesiclepedia_1164 | 29904572 | Bos taurus | A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. | Bovine milk |
Protein miRNA |
Differential centrifugation Density gradient centrifugation |
Extracellular vesicles | EVs |
547 | Vesiclepedia_335 | 20976003 | Homo sapiens | Selective release of microRNA species from normal and malignant mammary epithelial cells | Breast cancer cells |
Protein miRNA |
Differential centrifugation Filtration |
Exosomes | EVs |